Nontuberculous mycobacterial disease prevalence and risk factors: a changing epidemiology

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
P Maureen CassidyKevin L Winthrop

Abstract

Nontuberculous mycobacteria (NTM) are important human pathogens, yet little is known about disease prevalence in the United States. Reports suggest prevalence has increased, particularly in women, but population-based data to substantiate this are lacking. We sought to estimate NTM disease prevalence in Oregon, and describe disease by site, species, and patient demographic characteristics. We contacted laboratories that performed mycobacterial cultures on Oregon residents in 2005-2006. For each isolate, we obtained source, collection date, species, and patient demographics. We used the microbiologic component of the American Thoracic Society/Infectious Diseases Society of America's pulmonary NTM disease criteria to define cases of pulmonary NTM, and patients with isolates from a normally sterile site were classified as having extrapulmonary disease. We identified 933 patients with > or =1 NTM isolate. Of these, 527 (56%) met the case definition (annualized prevalence, 7.2 cases per 100,000 persons). Pulmonary cases predominated (5.6 cases per 100,000 persons), followed by skin/soft-tissue cases (0.9 cases per 100,000 persons). Mycobacterium avium complex was the most common species identified in pulmonary cases (4.7 cases per 1...Continue Reading

Citations

Jan 18, 2011·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·C-C LaiP R Hsueh
Jun 26, 2013·Nature Reviews. Rheumatology·Kevin L Winthrop, Michael D Iseman
Dec 12, 2012·Journal of Clinical Microbiology·Nandhakumar BalakrishnanEdward B Breitschwerdt
Jun 12, 2010·American Journal of Respiratory and Critical Care Medicine·D Rebecca PrevotsKenneth N Olivier
Dec 27, 2011·American Journal of Respiratory and Critical Care Medicine·Makoto HayashiYutaka Sugita
Nov 13, 2012·American Journal of Respiratory and Critical Care Medicine·Marinka KartalijaEdward D Chan
Oct 3, 2012·American Journal of Respiratory and Critical Care Medicine·Theodore K Marras
May 7, 2011·BMC Infectious Diseases·Gowri SatyanarayanaEric R Houpt
May 18, 2013·BMC Complementary and Alternative Medicine·Adelina Jiménez-ArellanesLilián Yépez-Mulia
Dec 18, 2013·BMC Research Notes·Iza Perez-MartinezJorge A Gonzalez-Y-Merchand
Jun 6, 2013·PLoS Neglected Tropical Diseases·Bright VargheseSahal Abdulaziz Al-Hajoj
Jul 23, 2013·PLoS Neglected Tropical Diseases·Ana Roberta Fusco da CostaKarla Valéria Batista Lima
Mar 12, 2011·Emerging Infectious Diseases·Brian A KendallKevin L Winthrop
Sep 6, 2011·Emerging Infectious Diseases·Kevin L WinthropKatrina Hedberg
Jan 20, 2012·Emerging Infectious Diseases·Seon Young KimEui-Chong Kim
Nov 12, 2013·Emerging Infectious Diseases·Theodore K MarrasFrances Jamieson
Nov 21, 2013·Annals of the American Thoracic Society·Kohei FujitaMichiaki Mishima
Oct 10, 2013·Annals of the American Thoracic Society·Kozo MorimotoShoji Kudoh
Apr 2, 2014·European Journal of Internal Medicine·Mehdi MirsaeidiJoseph O Falkinham
Jan 13, 2015·BioMed Research International·Mehdi MirsaeidiJoseph O Falkinham
Dec 3, 2014·Diagnostic Microbiology and Infectious Disease·Daniel P BoyleChao Qi
Dec 12, 2012·Mayo Clinic Proceedings·Ashley B WentworthChristine M Lohse
Sep 5, 2012·Enfermedades infecciosas y microbiología clínica·Inmaculada de Toro-PeinadoBegoña Palop-Borrás
Dec 23, 2015·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Chien-Fu YehAn-Suey Shiao
Dec 6, 2011·Diagnostic Microbiology and Infectious Disease·Chih-Cheng LaiPo-Ren Hsueh
Nov 6, 2015·Annals of the American Thoracic Society·Christopher A CzajaGary R Cott
Sep 3, 2010·Free Radical Biology & Medicine·Rebecca E Oberley-DeeganJames D Crapo
Sep 13, 2015·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Sheng BiJi-Fang Sheng

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Separation Anxiety

Separation anxiety is a type of anxiety disorder that involves excessive distress and anxiety with separation. This may include separation from places or people to which they have a strong emotional connection with. It often affects children more than adults. Here is the latest research on separation anxiety.

KIF1A Associated Neurological Disorder

KIF1A associated neurological disorder (KAND) is a rare neurodegenerative condition caused by mutations in the KIF1A gene. KAND may present with a wide range and severity of symptoms including stiff or weak leg muscles, low muscle tone, a lack of muscle coordination and balance, and intellectual disability. Find the latest research on KAND here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Related Papers

American Journal of Respiratory and Critical Care Medicine
Kevin L WinthropKatrina Hedberg
American Journal of Respiratory and Critical Care Medicine
D Rebecca PrevotsKenneth N Olivier
American Journal of Respiratory and Critical Care Medicine
Claire AndréjakReimar W Thomsen
American Journal of Respiratory and Critical Care Medicine
D E GriffithInfectious Disease Society of America
© 2021 Meta ULC. All rights reserved