Nonvisible tumors on multiparametric magnetic resonance imaging does not predict low-risk prostate cancer

Prostate International
Seung Hwan LeeByung Ha Chung

Abstract

To determine whether multiparametric MRI could help predict the diagnosis of low-risk prostate cancer (PCA). We retrospectively analyzed consecutive 623 patients with PCA who underwent multiparametric MRI before radical prostatectomy(RP). High-resolution T1- and T2-weighted, diffusion-weighted, and dynamic precontrast and postcontrast image sequences were obtained for each patient. Of the 623 patients, 177(28.4%) exhibited non visible tumors on MRI of clinical stage T1c. The imaging results were compared with the pathological findings with respect to both stage and Gleason scores (GS). Of the 177 prostatectomy patients with non visible tumors on MRI, pathological findings resulted in the upgrading of 49(27.7%) patients to a sum of GS 7 or more. 101(57.1%) patients exhibited tumor volumes greater than 0.5cc. The biochemical recurrence rate was significantly higher in the pathological upgraded group compared with the nonupgraded group after a mean follow-up time of 29 months. In the multiple logistic analysis, non visible tumor on MRI was not a significant predictor of low-risk PCA. Even though cancer foci were not visualized by postbiopsy MRI, the pathological tumor volumes and extent of GS upgrading were relatively high. Theref...Continue Reading

References

Jan 1, 1997·World Journal of Urology·H B Carter, J I Epstein
Sep 24, 2004·AJR. American Journal of Roentgenology·Aliya QayyumJohn Kurhanewicz
Jul 25, 2007·AJR. American Journal of Roentgenology·Masoom A HaiderJohn Trachtenberg
Feb 24, 2009·The Journal of Urology·Simon L ContiPeter R Carroll
Aug 18, 2009·European Urology·Guillaume PloussardAlexandre de la Taille
Nov 18, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Laurence KlotzAndrew Loblaw
Sep 24, 2010·Urologia Internationalis·Pietro PepeFrancesco Aragona
Jun 4, 2013·The Journal of Urology·Soroush Rais-BahramiPeter A Pinto

❮ Previous
Next ❯

Citations

Jun 11, 2016·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Henk G van der Poel, Roderick C N van den Bergh
Mar 7, 2019·Journal of Medical Imaging·Yohan SumathipalaRonald M Summers
Jul 7, 2021·International Journal of Urology : Official Journal of the Japanese Urological Association·Shunsuke MiyamotoAkio Matsubara

❮ Previous
Next ❯

Methods Mentioned

BETA
PCA
imaging
biopsy

Software Mentioned

SPSS

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.