PMID: 9165521Apr 1, 1997Paper

Noonan syndrome and moyamoya

Pediatric Neurology
V Ganesan, Fenella J Kirkham

Abstract

We report a patient with Noonan syndrome and asymptomatic cardiac disease (supravalvular aortic stenosis and pulmonary valvular stenosis) who had frequent transient ischemic attacks. Bilateral moyamoya was evident; in addition, he manifested activated protein C resistance and was heterozygous for the factor V Leiden mutation. Anticoagulation abolished his episodes and, despite extensive cerebrovascular disease, he has no permanent neurologic deficits. The association between Noonan syndrome and moyamoya has not previously been described. Disruption of vascular development in prenatal life may have resulted in both cardiac and cerebrovascular disease in this child.

References

Feb 1, 1992·Archives of Disease in Childhood·M SharlandM A Paton
Jan 1, 1992·Postgraduate Medical Journal·F SchonM Baraitser
Jan 1, 1983·Stroke; a Journal of Cerebral Circulation·J Suzuki, N Kodama

❮ Previous
Next ❯

Citations

Nov 3, 2004·Pediatric Neurology·Yushiro YamashitaToyojiro Matsuishi
Oct 6, 1998·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·J M LimalS Lyonnet
Jun 22, 2006·Journal of Neurology, Neurosurgery, and Psychiatry·Y MineharuA Koizumi
May 17, 2002·Brain & Development·Yoshiko IshiguroKazuyoshi Watanabe
Apr 3, 2007·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·Selina Y C HuneMeredith R Golomb
Apr 11, 2015·American Journal of Medical Genetics. Part a·Fu-Sung LoNi-Chung Lee
Jan 19, 2016·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Mihir GuptaGary K Steinberg
May 4, 2010·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Marta Lopez-VicenteMichel T Torbey
Dec 9, 2009·Advances in Pediatrics·Neil Friedman
Dec 15, 2015·Environmental Health and Preventive Medicine·Akio KoizumiShohab Youssefian
Oct 19, 2010·American Journal of Medical Genetics. Part a·Murat DerbentNamik Özbek
May 9, 2015·Human Mutation·Simone MartinelliMarco Tartaglia
Jul 19, 2011·Pediatric Neurology·Po-Cheng HungAlex M-C Wong
Jan 8, 2015·Pediatric Neurology·Jin-Ho ChoiHan-Wook Yoo
Jul 24, 2013·Journal of Child Neurology·Yuri A ZarateM Gisele Matheus
Apr 20, 2017·American Journal of Medical Genetics. Part a·Claudia SantoroSilverio Perrotta
Mar 4, 2009·Circulation·Catherine Amlie-LefondUNKNOWN International Pediatric Stroke Study Group
Apr 14, 2007·American Journal of Medical Genetics. Part a·Santhosh GirirajanSarah H Elsea
Nov 23, 2018·International Journal of Molecular Sciences·Sciacca Francesca LuisaBersano Anna
May 6, 2019·Bioengineering·Kimia Kamal, Ben Waldau
Mar 30, 2021·The Application of Clinical Genetics·Kirsten B Dorschel, John E Wanebo
Sep 21, 2021·Frontiers in Neurology·Brandon M FoxJohn E Wanebo
Jan 15, 2013·Lancet·Amy E RobertsBruce D Gelb

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Pediatric Neurology
Po-Cheng HungAlex M-C Wong
Pediatric Neurology
Takashi ShiiharaKiyoshi Hayasaka
Acta Neurologica Scandinavica
C MinelliB O Colli
© 2021 Meta ULC. All rights reserved