PMID: 7372353Jan 1, 1980Paper

Norepinephrine in urine and plasma following provocative maneuvers in normal and hypertensive subjects

Hypertension
D P HenryC E Grim

Abstract

Urinary norepinephrine (UNE) excretion rate and venous plasma norepinephrine (PNE) concentrations were studied in 266 normotensive and 107 essential hypertensive men and women under conditions of volume expansion with 2 liters of intravenous normal saline over 4 hours, and volume contraction with a 10 mEq sodium diet and 120 mg oral furosemide. The UNE excretion rate was correlated with age in normal women only. In men, and in hypertensives of both sexes, the relationship appeared to be biphasic. The PNE concentration was not correlated with age in the hypertensive subjects. Insufficient numbers of older subjects were available to exclude absolutely such a relationship among normals. The UNE and PNE were influenced by volume expansion and contraction in both normals and hypertensives; however, normals exhibited a correlation between UNE and blood pressure as well as consistent correlations between UNE and PNE, neither of which were observed in the hypertensives. Hypertensive women generally had greater UNE and PNE values than normal women or hypertensive men. Hypertensive women may have altered sympathetic activity.

References

Nov 1, 1977·Annals of Internal Medicine·J R MitchellF C Bartter
Oct 1, 1978·Archives of Internal Medicine·R HolleR A Stone
May 31, 1976·The American Journal of Medicine·N K Hollenberg, D F Adams
Jan 27, 1977·The New England Journal of Medicine·C R LakeI J Kopin
Feb 24, 1977·The New England Journal of Medicine·M EslerV DeQuattro
Sep 22, 1977·The New England Journal of Medicine·J De Champlain, D Cousineau
Nov 1, 1976·The American Journal of the Medical Sciences·O KuchelJ Genest
Feb 1, 1975·Life Sciences·D P HenryR H Williams
Jan 1, 1975·Endocrine Research Communications·J L CucheJ Genest
Feb 1, 1976·Circulation Research·J de ChamplainM R van Ameringen
Mar 2, 1972·The New England Journal of Medicine·H R BrunnerF R Bühler
Apr 1, 1970·Archives of Internal Medicine·A J Edis, J T Shepherd
Mar 22, 1973·The New England Journal of Medicine·W J LouisS Anavekar
Sep 1, 1971·Archives of Internal Medicine·D C KemC A Nugent
Oct 1, 1968·The Journal of Clinical Investigation·V DeQuattro, A Sjoerdsma
Dec 1, 1965·Japanese Circulation Journal·T Ikoma
Nov 1, 1967·Circulation Research·L R KrakoffJ Axelrod
Jan 1, 1954·Scandinavian Journal of Clinical and Laboratory Investigation·U S VON EULERA PURKHOLD
May 1, 1957·Journal of Clinical Pathology·W J GRIFFITHS, S COLLINSON
Jan 1, 1957·Scandinavian Journal of Clinical and Laboratory Investigation·P MOLLERE BIERRING
Mar 1, 1961·American Heart Journal·J R CROUTA SJOERDSMA
Oct 25, 1960·The Tohoku Journal of Experimental Medicine·K YOSHINAGAN ISHIDA
Apr 1, 1964·The American Journal of Cardiology·P A SERRANOA RAMIREZDELANGEL
Jul 16, 1964·The New England Journal of Medicine·S BRUNJES
Jan 1, 1955·Scandinavian Journal of Clinical and Laboratory Investigation·A PEKKARINEN, M E PITKANEN

❮ Previous
Next ❯

Citations

Mar 1, 1983·Journal of the Autonomic Nervous System·R H Johnson
Jan 1, 1986·Journal of the American College of Nutrition·F C LuftN S Fineberg
Jan 1, 1991·Clinical and Experimental Hypertension. Part A, Theory and Practice·A KinoshitaK Arakawa
Jan 1, 1981·Clinical and Experimental Hypertension : CHE·M H WeinbergerJ C Christian
Jan 1, 1981·Clinical and Experimental Hypertension : CHE·J de ChamplainG Denis
Jan 1, 1982·Clinical and Experimental Hypertension. Part A, Theory and Practice·M H WeinbergerD P Henry
May 1, 1982·The American Journal of the Medical Sciences·F C LuftM H Weinberger
Apr 1, 1993·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M H Weinberger
Nov 1, 1981·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·L I RankinF C Luft
Jan 26, 1987·The American Journal of Medicine·F C LuftC E Grim
Jan 1, 1983·Hypertension·A M ShepherdT K Keeton
Nov 1, 1981·Hypertension·L I RankinM H Weinberger
Feb 1, 1982·Circulation·T A KotchenJ M Kotchen
Mar 1, 1981·Circulation Research·N C Trippodo, E D Frohlich
Dec 1, 1989·Clinical Cardiology·M H Weinberger

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.