Norfloxacin detection based on the peroxidase-like activity enhancement of gold nanoclusters.

Analytical and Bioanalytical Chemistry
Yuying SongLi Qi

Abstract

The use of nanomaterials as mimic enzymes provides a promising way to implement bio-molecule detection in living systems. However, to achieve highly efficient catalytic processes with gold nanocluster-based nanozymes is still challenging. In this study, a facile reduction method was utilized to synthesize gold nanoclusters with 1-methyl-D-tryptophan as the reducing and capping agent. The obtained gold nanoclusters exhibited a peroxidase-mimicking property in the redox reaction of 3,3',5,5'-tetramethylbenzidine to blue oxidized 3,3',5,5'-tetramethylbenzidine in the presence of H2O2. The addition of norfloxacin endowed the nanozymes with a 10-fold enhancement in catalytic efficiency due to the surface charge-controlled electron transfer modulation. The colorimetric sensing system presented a high selectivity toward norfloxacin. The good linear relationship of norfloxacin monitoring was gained in the range of 1.25~8.0 μM (R2 = 0.996), with a detection limit of 0.2 μM. The practical application of the proposed protocol for the measurement of norfloxacin in capsules was realized. This demonstrates that on account of their significant catalytic efficiency enhancement, the gold nanocluster-based nanozymes hold great promise in realizi...Continue Reading

References

Aug 5, 2008·Microbial Ecology·Mindy G Brown, David L Balkwill
Mar 3, 2012·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Sheng WangXin-Hua Lin
Aug 4, 2015·Nanoscale·Biwu Liu, Juewen Liu
Oct 16, 2015·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Cassiana MendesMarcos Antônio Segatto Silva
Sep 25, 2018·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Mao Xia Guo, Yuan Fang Li
Nov 21, 2018·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Shima AbarghoeiMohammad Reza Ganjali
May 18, 2019·Analytical and Bioanalytical Chemistry·Zahra DehghaniMorteza Hosseini
May 18, 2019·Dalton Transactions : an International Journal of Inorganic Chemistry·Shan WangMeng Li

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