Normal ambulatory 24-hour esophageal pH values in Koreans -a multicenter study-.

Journal of Korean Medical Science
Gwang Ha KimHyo Jin Park

Abstract

Ambulatory 24-hr esophageal pH monitoring is considered the gold standard for diagnosing gastroesophageal reflux disease. The aim of this study was to establish normal values for gastroesophageal acid exposure in healthy Koreans. Fifty healthy volunteers (24 males and 26 females; mean age, 45 yr) without reflux symptoms and without reflux esophagitis or hiatal hernia on upper endoscopy underwent ambulatory 24-hr esophageal pH monitoring after esophageal manometry. The 95th percentiles for the reflux parameters were: the percent total time pH <4, 3.7%; the percent upright time pH <4, 5.7%; the percent supine time pH <4, 1.0%; the number of reflux episodes with pH <4, 76.5; the number of reflux episodes with pH <4 for >5 min, 1.5; the duration of the longest episode, 12.5 min; and the composite score, 14.2. Age and gender were not associated with any of the pH parameters. In conclusion, physiological gastroesophageal reflux occurs in healthy Koreans. These normal esophageal pH values will provide reference data for clinical and research studies in Korea.

References

Sep 1, 1988·Digestive Diseases and Sciences·G J WienerJ E Richter
Jan 1, 1986·Journal of Clinical Gastroenterology·L F Johnson, T R DeMeester
Oct 1, 1985·Gastroenterology·P K SchlesingerT J Layden
Sep 1, 1982·Scandinavian Journal of Gastroenterology·M KekkiM Siurala
Oct 12, 2001·Journal of Gastroenterology and Hepatology·J H KimUNKNOWN Korea H. pylori Study Group, South Korea
Jun 1, 1958·Proceedings of the Society for Experimental Biology and Medicine·S G TUTTLE, M I GROSSMAN
Jul 1, 1964·Archives of Surgery·F A MILLERT GUNTHER
Aug 11, 2005·The Kaohsiung Journal of Medical Sciences·Chih-Hsun YiMing-Cheh Chen

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Citations

Jun 11, 2010·Journal of Neurogastroenterology and Motility·Bong Eun LeeGeun Am Song
Jun 11, 2010·Journal of Neurogastroenterology and Motility·Gwang Ha Kim
Aug 11, 2010·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Yu Kyung ChoUNKNOWN Korean Society of Neurogastroenterology and Motility
Dec 19, 2018·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·R M L NetoM G Patti
Dec 31, 2020·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Seung Young KimHye Ah Lee
Oct 14, 2021·Journal of Neurogastroenterology and Motility·Hye-Kyung JungUNKNOWN Korean Society of Neurogastroenterology and Motility

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Software Mentioned

Polygram
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