PMID: 7546785Jul 1, 1995Paper

Normal changes in left ventricular filling and hemodynamics during dobutamine stress echocardiography

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
M TanimotoW Jintapakorn

Abstract

During high-dose dobutamine infusion, there is a dose-dependent increase in cardiac output, a reduction in systemic vascular resistance, a reduction in left ventricular size, an increase in the mitral A wave velocity, a reduction in the E/A velocity ratio, and a reduction in the isovolumic relaxation time, with little change in the rate-corrected isovolumic relaxation time. Left ventricular cavity obliteration is common. This information may be useful in defining the mechanism of hypotension commonly seen during dobutamine stress echocardiography. It is speculated that the diastolic behavior of the left ventricle during dobutamine stress echocardiography, especially the isovolumic relaxation time, may provide an additional indicator of early myocardial ischemia, but this needs to be confirmed by larger independent studies.

Citations

Dec 29, 2000·Journal of the American College of Cardiology·M L GeleijnseJ R Roelandt
Sep 1, 1997·Journal of the American College of Cardiology·M L GeleijnseJ R Roelandt
Jun 18, 1999·Annals of the New York Academy of Sciences·A W ScherhagD L Heene
Jan 26, 2008·Circulation Journal : Official Journal of the Japanese Circulation Society·Dae-Won SohnYun-Shik Choi
Mar 6, 1998·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·A Dabrowska-KugackaF E Rademakers
Aug 27, 1998·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·R B DaggubatiR G Pai
Jan 28, 2004·Journal of Magnetic Resonance Imaging : JMRI·Bernard P PaelinckAlbert de Roos

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