PMID: 16618979Apr 19, 2006Paper

Normal delivery following an uneventful pregnancy in a Japanese acromegalic patient after discontinuation of octreotide long acting release formulation at an early phase of pregnancy

Endocrine Journal
Tatsuro TakanoTetsuo Nishikawa

Abstract

We report a 35-year-old woman with active acromegaly despite pituitary surgery and irradiation who received continuous octreotide LAR treatment for the control of GH excess until discovery of her pregnancy. The patient delivered a healthy boy following an uneventful pregnancy after discontinuing octreotide LAR as soon as possible at the early phase of pregnancy. Despite a substantial maternal-fetal transfer of octreotide, postnatal development was normal at 3 years of age. In almost all previously described cases, octreotide was discontinued after pregnancy was confirmed. No side-effects of mother or fetus have been reported. Octreotide treatment in pregnancy seems to be feasible and safe. Due to the still-limited number of reported cases treated with octreotide LAR, the potential benefits of octreotide LAR treatment should be weighed carefully against its possible risks.

References

Sep 1, 1990·The Journal of Clinical Endocrinology and Metabolism·A BeckersF Frankenne
Nov 1, 1995·The Journal of Clinical Endocrinology and Metabolism·P M StewartM C Sheppard
Aug 31, 1995·The New England Journal of Medicine·P CaronL Pradayrol
Aug 1, 1996·Metabolism: Clinical and Experimental·I LancranjanL Simionescu
Aug 1, 1996·Metabolism: Clinical and Experimental·S W LambertsL J Hofland
Jan 1, 1996·Current Opinion in Oncology·A Chaudhry, L Kvols
Apr 16, 1998·Endocrinology and Metabolism Clinics of North America·M T McDermott, E C Ridgway
Sep 16, 1998·Lancet·M E CaplinA K Burroughs
Jan 8, 1999·Seminars in Perinatology·M E Molitch
Apr 20, 1999·Endocrinology and Metabolism Clinics of North America·C B Newman
Aug 10, 2000·Clinical Endocrinology·T HierlC Kasperk
Jun 26, 2001·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·J M Neal
Oct 9, 2001·Clinical Endocrinology·M FassnachtB Allolio
Mar 13, 2002·Mayo Clinic Proceedings·Nasser Mikhail

❮ Previous
Next ❯

Citations

Jan 12, 2011·Pituitary·Jean-Christophe MaizaPhilippe Caron
Jul 27, 2011·Pituitary·Vicky ChengAmir Hamrahian
Nov 26, 2011·Best Practice & Research. Clinical Endocrinology & Metabolism·Zuleyha Karaca, Fahrettin Kelestimur
Sep 23, 2009·Clinical Endocrinology·Pietro MaffeiNicola Sicolo
Aug 29, 2016·Pituitary·Ammar MuhammadAart J van der Lely
Mar 16, 2017·European Journal of Endocrinology·Julio AbuchamMonike L Dias
Aug 12, 2016·Obstetric Medicine·Angela AssalErin Keely
Mar 27, 2018·Clinical Endocrinology·R S JalladM D Bronstein
Jan 31, 2019·Expert Review of Endocrinology & Metabolism·Philippe ChansonPhilippe Caron
Jan 14, 2012·Endocrine Journal·Leandro KasukiMônica R Gadelha
Sep 15, 2019·Clinical Endocrinology·Magaly VialonPhilippe J Caron
Jun 22, 2017·Journal of Endocrinological Investigation·Z KaracaF Kelestimur
Oct 18, 2007·Current Opinion in Endocrinology, Diabetes, and Obesity

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Archives of Gynecology and Obstetrics
Michi HisanoKoushi Yamaguchi
Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association
A AtmacaT Erbas
European Journal of Endocrinology
Renato CozziMichela Barausse
Clinical Endocrinology
T HierlC Kasperk
© 2022 Meta ULC. All rights reserved