Normal left ventricular function

Circulation
J O Parker, R B Case

Abstract

The Starling relationship in the normal human ventricle may be different than usually portrayed. In normal, resting, supine man the ventricular function curve is at its peak at a left ventricular end-diastolic pressure of approximately 10 mm Hg. Below this point is a strong direct relation between filling pressure and stroke work, while at higher filling pressures, a plateau occurs. Limitation of ventricular response is related to a sharply rising ventricular pressure-volume curve at a normal level of filling pressure. Thus, in the supine position, the normal heart is not on the active portion of the ventricular function curve, but is in a unique position in which cardiac output is probably controlled by factors other than ventricular filling pressure. In ventricular failure, the peak of the ventricular function curve is displaced to a higher level.

References

Jan 1, 1978·The American Journal of Cardiology·U Thadani, J O Parker
Apr 1, 1978·The American Journal of Cardiology·M J MortonS H Rahimtoola
Jan 1, 1978·Catheterization and Cardiovascular Diagnosis·G W Burggraf, J O Parker
Aug 1, 1976·The American Journal of Cardiology·J O ParkerP W Armstrong
Jul 1, 1973·Cardiovascular Research·A A WalkerC E Rackley
Dec 13, 1973·The New England Journal of Medicine·C CrexellsH J Swan
Jun 1, 1971·Circulation·F KhajaJ O Parker
Aug 1, 1970·The Journal of Clinical Investigation·R O RussellH T Dodge
Jan 1, 1954·Circulation Research·R F RUSHMER
Jul 1, 1959·Circulation Research·R F RUSHMERD FRANKLIN
May 1, 1961·The American Journal of Medicine·S J SARNOFF, J H MITCHELL
Feb 1, 1960·The American Journal of Physiology·D M GRIGGSR B CASE
Oct 1, 1961·The Journal of Clinical Investigation·E BRAUNWALDJ ROSS
Jan 1, 1964·Angiology·A G WARER STRAGNELL
Sep 1, 1964·The American Journal of Physiology·V S BISHOPA C GUYTON
Jan 1, 1965·British Heart Journal·E BRAUNWALD
Sep 8, 1914·The Journal of Physiology·S W Patterson, E H Starling

❮ Previous
Next ❯

Citations

Jan 1, 1980·Annals of Biomedical Engineering·K Sagawa
May 1, 1982·The American Journal of Cardiology·P FiorettiF Camerini
Jan 1, 1982·Comparative Biochemistry and Physiology. A, Comparative Physiology·Z J Penefsky, W N Scott
Sep 29, 1999·Transplantation Proceedings·F AcostaP Parrilla
Mar 1, 1984·Journal of the American College of Cardiology·S S AhmedT J Regan
Dec 1, 1986·Journal of the American College of Cardiology·P AnversaG Olivetti
Dec 18, 2003·Clinical and Experimental Pharmacology & Physiology·Fiona J SutherlandDavid J Hearse
Mar 30, 2010·Acta Physiologica·C G Crandall, J González-Alonso
May 7, 2009·The Journal of Physiology·T E WilsonC G Crandall
Apr 30, 2005·The Journal of Physiology·Stefan P MortensenJosé González-Alonso
Dec 1, 1985·The American Journal of Cardiology·J V NixonJ H Mitchell
May 15, 1983·The American Journal of Cardiology·S Colan
Sep 1, 1987·The American Journal of Cardiology·M WishA I Cohen
Apr 1, 1981·Seminars in Nuclear Medicine·J P WexlerM D Blaufox
Jan 1, 1986·American Heart Journal·D L MannA A Bove
Oct 1, 1986·Clinical Cardiology·P KoskinenJ Heikkilä
Jul 14, 2001·Critical Care Clinics·K Cruz, C Franklin
Jul 1, 1982·American Heart Journal·S D Colan
Feb 10, 1999·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·T OkiS Ito
Aug 1, 2018·Intensive Care Medicine Experimental·María C Arango-GranadosLuis A Bustamante Cristancho
Nov 16, 2001·American Journal of Physiology. Heart and Circulatory Physiology·T D MooreI Belenkie
Feb 9, 2000·American Journal of Physiology. Heart and Circulatory Physiology·J González-AlonsoE F Coyle

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.