PMID: 9171968May 1, 1997Paper

Normal levels of energy expenditure in patients with reported "low metabolism'

Clinical Physiology
A R SkovA Astrup

Abstract

The present study examined the hypothesis that patients with apparent diet-resistant obesity have subnormal energy expenditure. Ten biochemically euthyroid patients (eight women and two men), aged 21-76 years, with either excessive gynoid fat distribution or obesity (BMI 23.8-41.0), were referred to the department thought to be suffering from a low metabolic rate syndrome since dietary records showed very low energy intake (< 5 MJ day-1) in combination with failure to lose weight on low-energy diets. Twenty-four-hour energy expenditure (24-h EE), basal energy expenditure (BEE) and sleeping energy expenditure (SEE) were measured in a respiration chamber on a fixed activity programme. The patients consumed a diet containing 37 energy-per cent (E%) fat, 47 E% carbohydrate and 16 E% protein. The individual energy intake was estimated from a previously established algorithm between 24-h EE and fat-free mass (FFM) estimated by bioimpedance. Results were compared with equivalent values in a reference population of 76 subjects ranging from normal weight to obese. No evidence of low metabolism was found in terms of adjusted 24-h EE in the patients with diet resistance when compared with the control group (9263 +/- 819 kJ vs. 9211 +/- 55...Continue Reading

References

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Citations

Apr 22, 2003·Environmental Technology·Y H SongH X Tang
Nov 24, 1999·Current Opinion in Clinical Nutrition and Metabolic Care·C L Reid, G L Carlson
Aug 29, 2002·Gastroenterology·Samuel KleinHarvey J Sugerman

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