PMID: 6844400Mar 1, 1983

Normal levels of total body sodium and chlorine by neutron activation analysis

Physics in Medicine and Biology
N S KennedyP Tothill


In vivo neutron activation analysis was used to measure total body sodium and chlorine in 18 male and 18 female normal adults. Corrections for body size were developed. Normalisation factors were derived which enable the prediction of the normal levels of sodium and chlorine in a subject. The coefficient of variation of normalised sodium was 5.9% in men and 6.9% in women, and of normalised chlorine 9.3% in men and 5.5% in women. In the range examined (40-70 years) no significant age dependence was observed for either element. Total body sodium was correlated with total body chlorine and total body calcium. Sodium excess, defined as the amount of body sodium in excess of that associated with chlorine, also correlated well with total body calcium. In females there was a mean annual loss of sodium excess of 1.2% after the menopause, similar to the loss of calcium.


Mar 1, 1979·The British Journal of Radiology·J R WilliamsC J Parnell
Feb 1, 1978·Clinical Science and Molecular Medicine·K BoddyE D Williams
Jun 1, 1976·Metabolism: Clinical and Experimental·K J EllisS H Cohn
Jan 1, 1972·British Medical Journal·D J HoskingH James
May 1, 1982·Physics in Medicine and Biology·N S KennedyP Tothill
May 1, 1982·Physics in Medicine and Biology·T J Spinks, D K Bewley
Jun 1, 1956·The Journal of Clinical Investigation·G B FORBES, A M LEWIS


Sep 1, 1984·Physics in Medicine and Biology·D R Chettle, J H Fremlin
Jul 27, 1989·The New England Journal of Medicine·A BaranovL Petrosyan
Feb 1, 1987·Physics in Medicine and Biology·A H BeddoeG L Hill
Nov 1, 1984·Physics in Medicine and Biology·R H Mole

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