Normal values of native T1 and T2 relaxation times on 3T cardiac MR in a healthy pediatric population aged 9-18 years.

Journal of Magnetic Resonance Imaging : JMRI
Marzena Barczuk-FalęckaMichał Brzewski

Abstract

Native myocardial T1 and T2 relaxation times are diagnostic tools used in clinical practice for adult and pediatric populations. Use of a mapping technique requires accurate knowledge of normal ranges in healthy patients, which is lacking in pediatric populations. To establish normal values for native T1 and T2 mapping in healthy pediatric subjects of different ages and sex. Prospective. Thirty-eight healthy children (9-18 years; mean age 14.0 ± 2.7). Cardiac MR with a 3T scanner. T1 and T2 mapping using MyoMaps software. T1 and T2 relaxation times were calculated from a 0.7-1.0 cm2 region of interest placed at the mid-ventricular short-axis slice in the interventricular septum by two observers. Inter- and intraobserver variability was assessed. The Student's t-test or the Mann-Whitney test for unpaired samples was applied to compare one continuous variable between two category groups. One-way analysis of variance (ANOVA) or a Kruskal-Wallis test was applied to compare one continuous variable between three category groups. Correlation between two continuous variables was assessed with a Pearson or Spearman test. The mean native T1 relaxation time was 1223 ± 29 msec and T2 relaxation time was 43 ± 4.5 msec. There was no correlat...Continue Reading

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Citations

Oct 3, 2020·Pediatric Cardiology·Tarek AlsaiedMichael D Taylor
Dec 23, 2020·Journal of Developmental Origins of Health and Disease·G D ClarkeP W Nathanielsz
Mar 30, 2021·Radiology. Cardiothoracic Imaging·Joseph J PaganoLars Grosse-Wortmann

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