PMID: 11903395Mar 21, 2002Paper

Normalization of pregnancy outcome in pregestational diabetes through functional insulin treatment and modular out-patient education adapted for pregnancy

Diabetic Medicine : a Journal of the British Diabetic Association
K HoworkaM Langer

Abstract

To investigate whether modular out-patient group education for flexible, Functional Insulin Treatment (FIT) adapted for pregnancy can eliminate diabetes-associated neonatal complications in pregestational diabetes. Outcome analysis of the modular out-patient group education and FIT based on separate insulin dosages for fasting, eating or correcting hyperglycaemia in 76 consecutive pregnancies (in 20 cases first after conception) of 59 patients with pregestational diabetes (Type 1 diabetes, n = 54). (a) diabetic pregnancies: historical controls; (b) non-diabetic pregnancies: retrospective case-controlled study; (c) population-based data of all Austrian newborns registered within the respective time period. HbA1c of 113 +/- 18% of mean value (= 100%) of non-diabetic, non-pregnant population (103 +/- 14% during the last pregnancy trimester), and self-monitored blood glucose of 5.6 +/- 0.7 mmol/l (5.3 +/- 0.7 mmol/l during the last trimester) was achieved throughout all FIT pregnancies. Severe hypoglycaemia occurred in 14 pregnancies. The gestational age at delivery was 39.2 +/- 1.5 weeks (four cases (5.4%) < 37 weeks) with a birth weight of 3305 +/- 496 g. Four newborns (5.3%) were above the 90th, and nine (11.8%) below the 10th p...Continue Reading

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Citations

May 8, 2002·Diabetes/metabolism Research and Reviews
Feb 22, 2012·Medizinische Klinik, Intensivmedizin und Notfallmedizin·B HarbeckF Sayk
Jun 2, 2005·Seminars in Fetal & Neonatal Medicine·Stephen A Walkinshaw
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Jun 22, 2007·Vojnosanitetski pregled. Military-medical and pharmaceutical review·Aleksandar Cetković, Marina Durović
May 16, 2014·Canadian Journal of Diabetes·David ThompsonChristina Vinokuroff
Jan 24, 2008·Journal of Evaluation in Clinical Practice·A A ElnourJames C McElnay
Oct 22, 2013·Diabetes Research and Clinical Practice·Anna L SecherLene Ringholm
Jul 21, 2010·Biomedical Engineering Online·José L OrtizPablo R Olmos
Jul 29, 2006·Diabetes Care·Rosemary C TempleHelen R Murphy
Apr 1, 2017·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Birgit HarbeckFriedhelm Sayk
Jun 12, 2017·The Cochrane Database of Systematic Reviews·Foong Ming MoyHelen M West
May 24, 2019·The Cochrane Database of Systematic Reviews·Leanne V JonesBrian S Buckley
Nov 26, 2008·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Ohad CohenEyal Sivan
Nov 15, 2017·International Journal of Clinical Pharmacy·Razan Adnan BattaAbla Albsoul-Younes
Feb 7, 2021·International Journal of Nursing Studies·Katelyn SushkoDiana Sherifali
Jul 5, 2021·BJOG : an International Journal of Obstetrics and Gynaecology·O KgosidialwaUNKNOWN INSPIRED Research Group

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