Normalized cut group clustering of resting-state FMRI data.

PloS One
Martijn van den HeuvelHilleke Hulshoff Pol

Abstract

Functional brain imaging studies have indicated that distinct anatomical brain regions can show coherent spontaneous neuronal activity during rest. Regions that show such correlated behavior are said to form resting-state networks (RSNs). RSNs have been investigated using seed-dependent functional connectivity maps and by using a number of model-free methods. However, examining RSNs across a group of subjects is still a complex task and often involves human input in selecting meaningful networks. We report on a voxel based model-free normalized cut graph clustering approach with whole brain coverage for group analysis of resting-state data, in which the number of RSNs is computed as an optimal clustering fit of the data. Inter-voxel correlations of time-series are grouped at the individual level and the consistency of the resulting networks across subjects is clustered at the group level, defining the group RSNs. We scanned a group of 26 subjects at rest with a fast BOLD sensitive fMRI scanning protocol on a 3 Tesla MR scanner. An optimal group clustering fit revealed 7 RSNs. The 7 RSNs included motor/visual, auditory and attention networks and the frequently reported default mode network. The found RSNs showed large overlap wi...Continue Reading

References

Mar 1, 1994·Journal of Computer Assisted Tomography·D L CollinsA C Evans
Jan 1, 1993·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·K J FristonR S Frackowiak
Oct 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·B BiswalJ S Hyde
Jun 22, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·X GolayP Boesiger
Feb 24, 2001·Proceedings of the National Academy of Sciences of the United States of America·M E RaichleG L Shulman
Oct 5, 2001·Nature Reviews. Neuroscience·D A GusnardM E Raichle
Aug 8, 2002·Magnetic Resonance Imaging·Dietmar CordesKen Maravilla
Dec 31, 2002·Proceedings of the National Academy of Sciences of the United States of America·Michael D GreiciusVinod Menon
Jun 20, 2003·NeuroImage·Vesa KiviniemiOsmo Tervonen
Apr 9, 2004·Proceedings of the National Academy of Sciences of the United States of America·Michael D GreiciusVinod Menon
Jun 26, 2004·Science·György Buzsáki, Andreas Draguhn
Jun 15, 2005·Human Brain Mapping·Serge A R B RomboutsPhilip Scheltens
Aug 10, 2005·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Raymond SalvadorEd Bullmore
Aug 10, 2005·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Christian F BeckmannStephen M Smith
Sep 1, 2005·NeuroImage·Bertrand ThirionJean-Baptiste Poline
Aug 1, 2006·Schizophrenia Research·Sifis MicheloyannisMichael Zervakis
Sep 2, 2006·Proceedings of the National Academy of Sciences of the United States of America·J S DamoiseauxC F Beckmann
Jan 20, 2007·Science·Malia F MasonC Neil Macrae
Mar 3, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·William W SeeleyMichael D Greicius
Mar 21, 2007·NeuroImage·Randy L Buckner, Justin L Vincent
May 12, 2007·Schizophrenia Bulletin·Peter Williamson
Jun 2, 2007·Magnetic Resonance Imaging·Nicolle CorreaVince D Calhoun
Jun 16, 2007·Science·Robert T Knight
Jun 20, 2007·Proceedings of the National Academy of Sciences of the United States of America·Nico U F DosenbachSteven E Petersen
Aug 21, 2007·Nature Reviews. Neuroscience·Michael D Fox, Marcus E Raichle
Aug 28, 2007·NeuroImage·Marcus E Raichle, Abraham Z Snyder
Sep 29, 2007·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Jaap C ReijneveldCornelis J Stam
Oct 13, 2007·NeuroImage·Jarkko Ylipaavalniemi, Ricardo Vigário
Dec 8, 2007·Cerebral Cortex·J S DamoiseauxS A R B Rombouts

❮ Previous
Next ❯

Citations

May 17, 2014·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Sharon Chiang, Zulfi Haneef
Feb 7, 2014·Neuropsychology Review·Martijn P van den Heuvel, Alex Fornito
Jun 15, 2014·Magnetic Resonance Imaging·Xiaomu Song, Nan-kuei Chen
Dec 3, 2014·Neuroimaging Clinics of North America·Mudassar KamranJoshua S Shimony
Sep 1, 2012·AJNR. American Journal of Neuroradiology·M H LeeJ S Shimony
Feb 18, 2009·Cerebral Cortex·Zarrar ShehzadMichael P Milham
Nov 26, 2009·Journal of Integrative Neuroscience·Peter A Bandettini
Nov 26, 2010·Cerebral Cortex·Ben DeenKevin A Pelphrey
Dec 17, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Mohamed L SeghierCathy J Price
Oct 26, 2012·Computational Intelligence and Neuroscience·E W LangC G Puntonet
Oct 16, 2012·Neuroinformatics·Bao GeTianming Liu
Oct 5, 2011·Cerebral Cortex·Xi-Nian ZuoMichael P Milham
Jan 26, 2012·Cerebral Cortex·Elisa MolinariCarlo A Porro
Apr 12, 2012·Cerebral Cortex·Dajiang ZhuTianming Liu
Aug 1, 2012·Neurology Research International·Katja KolleweBahram Mohammadi
Jun 1, 2013·Nature Methods·R Cameron CraddockMichael P Milham
Jun 15, 2011·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Cristina Rosazza, Ludovico Minati
May 18, 2010·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Martijn P van den Heuvel, Hilleke E Hulshoff Pol
May 20, 2015·NeuroImage·Wessel O van DamRutvik H Desai
Feb 3, 2009·Brain and Cognition·Michael C Stevens
Apr 3, 2009·Annals of the New York Academy of Sciences·Peter A Bandettini
Apr 8, 2016·Medical Image Analysis·Tuo ZhangTianming Liu

❮ Previous
Next ❯

Software Mentioned

Freesurfer
MALTAB
Ncutclustering
fcMap
SPM2

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.