Normalizing resting energy expenditure across the life course in humans: challenges and hopes

European Journal of Clinical Nutrition
Manfred James MüllerAnja Bosy-Westphal

Abstract

Whole-body daily energy expenditure is primarily due to resting energy expenditure (REE). Since there is a high inter-individual variance in REE, a quantitative and predictive framework is needed to normalize the data. Complementing the assessment of REE with data normalization makes individuals of different sizes, age, and sex comparable. REE is closely correlated with body mass suggesting its near constancy for a given mass and, thus, a linearity of this association. Since body mass and its metabolic active components are the major determinants of REE, they have been implemented into allometric modeling to normalize REE for quantitative differences in body weight and/or body composition. Up to now, various size and allometric scale laws are used to adjust REE for body mass. In addition, the impact of the anatomical and physical properties of individual body components on REE has been quantified in large populations and for different age groups. More than 80% of the inter-individual variance in REE is explained by FFM and its composition. There is evidence that the impact of individual organs on REE varies between age groups with a higher contribution of brain and visceral organs in children/adolescents compared with adults wh...Continue Reading

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Nov 7, 2015·The Proceedings of the Nutrition Society·Manfred J MüllerAnja Bosy-Westphal

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Citations

Jul 7, 2018·European Journal of Clinical Nutrition·Diana M ThomasDale A Schoeller
Oct 17, 2018·European Journal of Clinical Nutrition·Manfred J MüllerAnja Bosy-Westphal
Jul 31, 2019·Nutrition & Diabetes·James ReneauSrividya Kidambi
Sep 7, 2018·European Journal of Clinical Nutrition·M J Soares, M J Müller
Jul 22, 2018·F1000Research·Manfred J MüllerAnja Bosy-Westphal
Jun 27, 2019·American Journal of Medical Genetics. Part a·Andrea MadsenHanne B Slettahjell
Nov 7, 2019·Current Diabetes Reports·Manfred James Müller, Anja Bosy-Westphal
Jul 15, 2020·American Journal of Human Biology : the Official Journal of the Human Biology Council·Ana Cláudia Rossini VenturiniDalmo Roberto Lopes Machado
Oct 5, 2020·European Journal of Applied Physiology·Heather M BowesNigel A S Taylor
Dec 15, 2020·Journal of the International Society of Sports Nutrition·Tatiana MoroAntonio Paoli
Feb 15, 2020·Experimental Gerontology·Jasper Most, Leanne Maree Redman
Sep 2, 2018·American Journal of Obstetrics and Gynecology·Jasper Most, Leanne M Redman
Apr 9, 2021·Frontiers in Physiology·Petra Frings-MeuthenJörn Rittweger
May 8, 2021·American Journal of Human Biology : the Official Journal of the Human Biology Council·Lacey M GouldAbbie E Smith-Ryan
May 19, 2021·Obesity·Anja Bosy-WestphalManfred J Müller
Jun 17, 2021·The American Journal of Clinical Nutrition·Manfred J MüllerAnja Bosy-Westphal

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