PMID: 3215293Dec 1, 1988Paper

Nosocomial legionella pneumonia: demonstration of potable water as the source of infection

Epidemiology and Infection
B RufH D Pohle

Abstract

From January 1983 until December 1985, 35 cases of sporadic nosocomial legionella pneumonia, all caused by Legionella pneumophila, were diagnosed in a university hospital. L. pneumophila serogroup (SG) 1 was cultured from 12 of the 35 cases and compared to corresponding L. pneumophila SG 1 isolates from water outlets in the patients' immediate environment by subtyping with monoclonal antibodies. The corresponding environmental isolates were identical to 9 out of 12 (75%) of those from the cases. However, even in the remaining three cases identical subtypes were found distributed throughout the hospital water supply. From the hospital water supply four different subtypes of L. pneumophila SG 1 were isolated, three of which were implicated in legionella pneumonia. Of 453 water samples taken during the study 298 (65.8%) were positive for legionellae. Species of Legionella other than L. pneumophila have not been isolated. This may explain the exclusiveness of L. pneumophila as the legionella pneumonia-causing agent. Our results suggest that the water supply system was the source of infection.

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Citations

Aug 1, 1990·Epidemiology and Infection·M Castellani PastorisP Goldoni
Apr 1, 1992·Epidemiology and Infection·T J MarrieR Peppard
Apr 1, 1994·Epidemiology and Infection·C A JosephC L Bartlett
Oct 22, 2008·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Alexandre BrûletPhilippe Vanhems
Dec 30, 1999·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·J L KoolB S Fields
Jul 31, 2003·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Douglas B NelsonUNKNOWN Society for Healthcare Epidemiology of America
Oct 1, 1995·Journal of Industrial Microbiology·J RogersC W Keevil
Feb 18, 2003·Journal of Oral Rehabilitation·M OzcanE Kazazoglu
Jul 1, 1994·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·P C LückM Ott
Oct 23, 1997·Clinical Microbiology Reviews·W A Rutala, D J Weber
Aug 1, 1991·Applied and Environmental Microbiology·M Alary, J R Joly

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