Nosocomial multidrug-resistant Acinetobacter baumannii in the neonatal intensive care unit in Gaza City, Palestine

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
Abdel Moati Kh Al JaroushaIyad A El Qouqa

Abstract

We performed a prospective case-control study of bloodstream infections in order to determine the infection rate of Acinetobacter baumannii and to determine the risk factors associated with infection and mortality. Between February 2004 and January 2005, 579 consecutive blood specimens were collected from the two neonatal intensive care units (NICUs) of Al-Nasser and Al-Shifa hospitals in Gaza City. Forty (6.9%) isolates of A. baumannii were obtained from neonates aged under 28 days. Of the patients, 62.5% were male and 37.5% were female. Compared to matched, uninfected controls, statistically significant risk factors were weight<1500 g (odds ratio (OR) 3.89, p<0.001), age <7 days (OR 2.33, p=0.027), median hospitalization of =20 days (OR 3.1, p=0.003), mechanical ventilation (OR 3.5, p=0.001), use of a central venous catheter (CVC; OR 10.5, p<0.001), and prior antibiotic use (OR 4.85, p=0.003). The overall mortality was also significantly different (overall mortality 37.5% in cases vs. 12% in uninfected controls; OR 4.4, p=0.001). Compared to infected controls, statistically significant risk factors were mechanical ventilation (OR 2.68, p=0.008), use of a CVC (OR 6.68, p<0.001), and prior antibiotic use (OR 5.68, p=0.001). The...Continue Reading

References

Apr 1, 1983·The Journal of Infectious Diseases·D A GoldmannW A Durbin
Jan 1, 1997·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J F Acar
Jun 18, 1998·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D H Forster, F D Daschner
Apr 29, 1999·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·L CorderoL W Ayers
May 18, 1999·Archives of Disease in Childhood. Fetal and Neonatal Edition·J RoyleD Isaacs
Jan 22, 2000·The Pediatric Infectious Disease Journal·S B BrodieD K Richardson
Sep 23, 2000·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·E M D'AgataW Schaffner
Jan 4, 2001·Journal of Clinical Microbiology·A SimhonM Shapiro
Dec 24, 2002·The Journal of Hospital Infection·R MelamedR Dagan
Jan 9, 2003·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Naomi P O'GradyUNKNOWN Healthcare Infection Control Practices Advisory Committee
May 3, 2003·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Maria Virginia Villegas, Alan I Hartstein
Mar 1, 2006·Indian Journal of Medical Microbiology·K Prashanth, S Badrinath
Apr 17, 2007·American Journal of Infection Control·Bai-Horng SuHung-Chih Lin

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Citations

Sep 1, 2012·The Pediatric Infectious Disease Journal·Anucha ThatrimontrichaiGunlawadee Maneenil
Dec 3, 2014·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Hsiu-Mei WeiKao-Pin Hwang
Nov 2, 2013·American Journal of Infection Control·Jen-Fu HsuMing-Horng Tsai
May 25, 2011·Pediatrics International : Official Journal of the Japan Pediatric Society·Zhangxue HuYuan Shi
Sep 26, 2015·Journal of the Pediatric Infectious Diseases Society·Kirsty Le DoareMike Sharland
Nov 13, 2010·Neonatal Network : NN·Patricia Scheans
Oct 17, 2018·BMJ : British Medical Journal·Rupa KanapathipillaiMalika Saim
Oct 27, 2010·Journal of Paediatrics and Child Health·Tinuade A OgunlesiDurotoye M Olanrewaju
Oct 11, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Richard ChawanaShabir A Madhi
Jul 1, 2010·Expert Review of Anti-infective Therapy·Jaffar A Al-TawfiqZiad A Memish
Apr 7, 2018·The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Médicale·Mohammed K AlmaghrabiMohamed E Hamid
Oct 12, 2018·Current Infectious Disease Reports·Raffaele ZarrilliMaria Triassi
Jun 6, 2020·Indian Journal of Pediatrics·Capan KoncaMehmet Geyik

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