Nosocomial transmission of tuberculosis in two hospitals for mentally handicapped patients

Journal of the Formosan Medical Association = Taiwan Yi Zhi
Han-Yu HuangJen-Jyh Lee

Abstract

An unexpected significant increase in the number of tuberculosis (TB) cases in one hospital for mentally handicapped patients in eastern Taiwan was observed in early 2002. An active screening program was performed to identify undetected TB cases and to investigate nosocomial transmission of TB in two hospitals for mentally handicapped patients in eastern Taiwan. Active chest X-ray (CXR) screening followed by passive symptom screening were used to identify patients with pulmonary TB over 2 years in hospital A and B. IS 6110 restriction fragment length polymorphism and spacer oligonucleotide typing (spoligotyping) profiles of the isolates, clinical record of each case, TB control policies of the two hospitals, and risk factors of nosocomial transmission were analyzed. A total of 94.8% (2298/2423) inmates in hospital A and 96.3% (1902/1975) inmates in hospital B were screened by CXR at the beginning of 2002. During the 2-year study period, TB was diagnosed by sputum cultures for 30 patients in hospital A (notified disease rate = 619 per 100,000 population per year) and eight patients in hospital B (notified disease rate = 203 per 100,000 population per year). Seventeen patients (56.7%) in hospital A had six cluster pattern strains...Continue Reading

References

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Citations

May 13, 2010·BMC Public Health·Ching-Hsiung LinWoei-Horng Chai
Aug 21, 2010·The American Journal of the Medical Sciences·Tun-Chieh ChenYen-Hsu Chen
Feb 14, 2012·The Journal of Infection·Ewa Augustynowicz-KopećZofia Zwolska
Dec 24, 2015·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Sheng-Wei PanWei-Juin Su

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