PMID: 9442358Jan 27, 1998Paper

Not all myofibroblasts are alike: revisiting the role of PDGF-A and PDGF-B using PDGF-targeted mice

Current Opinion in Nephrology and Hypertension
P Lindahl, C Betsholtz

Abstract

Analyses of platelet-derived growth factor (PDGF) and PDGF-receptor knockout mice show that the development of specific subsets of smooth muscle cells (SMCs) depend on PDGF. Pericytes and mesangial cells failed to develop in PDGF-B deficient embryos, whereas alveolar SMCs failed to develop in PDGF-A deficient embryos. The ontogeny of pericytes and alveolar SMCs suggests a common theme in the formation of PDGF-dependent SMCs, in which PDGF-receptor positive SMC progenitors spread from proximal to distal sites along PDGF-expressing epithelial, or endothelial, tubes.

References

Feb 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·B J SilverH E Abboud
Nov 1, 1988·The American Journal of Physiology·M M Atkinson, J D Sheridan
Jan 1, 1986·Tissue & Cell·D E Sims
Dec 27, 1996·Cell·J Folkman, P A D'Amore

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Citations

Oct 23, 2001·Developmental Dynamics : an Official Publication of the American Association of Anatomists·U OzerdemW B Stallcup
Oct 8, 2005·Angiogenesis·P G GroothuisR Grümmer
Nov 13, 1998·Current Opinion in Lipidology·P LindahlC Betsholtz
Nov 28, 2013·Antioxidants & Redox Signaling·Alessandro Siani, Nicola Tirelli
Nov 10, 2009·International Journal of Radiation Biology·Stephan A SchmidLeoni A Kunz-Schughart
Jul 6, 2010·Developmental Biology·Feng-Ju HuangWilliam B Stallcup
Jan 5, 2005·The Journal of Clinical Investigation·Xuri LiPeter Carmeliet
Oct 19, 2017·International Journal of Molecular Sciences·Dominik André-LévigneBrigitte Pittet-Cuénod
May 12, 2000·Nature Cell Biology·X LiU Eriksson
Feb 4, 2014·Journal of Biomedical Materials Research. Part a·Nuno AlexandreAna Lúcia Luís
Dec 1, 2004·The Journal of Cell Biology·Michail S DavidoffDieter Müller
Dec 19, 2007·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Renée DickieAkira Tsuda
Apr 29, 2009·Journal of Cellular and Molecular Medicine·Alejandro RodriguezChristian Sundberg
Jul 1, 2009·International Journal of Experimental Pathology·Nicola SmartPaul R Riley
May 4, 2002·Nature Reviews. Molecular Cell Biology·James J TomasekRobert A Brown
Jun 19, 2008·The Journal of Biological Chemistry·Shinya YamamotoSatoshi Fukumoto
Jan 15, 2002·American Journal of Physiology. Heart and Circulatory Physiology·Jose A NadalA Guillermo Scicli
Jul 22, 1999·Experimental Cell Research·G Serini, G Gabbiani
Jun 23, 2004·Cytokine & Growth Factor Reviews·Michelle Tallquist, Andrius Kazlauskas
Jun 19, 2007·Experimental Cell Research·Stephan A SchmidLeoni A Kunz-Schughart

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