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Notch pathway in ependymoma RELA-fused subgroup: upregulation and association with cancer stem cells markers expression

Cancer Gene Therapy

Jul 17, 2019

Taciani de Almeida MagalhãesKleiton Silva Borges

Abstract

RELA-fused supratentorial (ST) ependymoma (EPN) is an aggressive subgroup with poor prognosis. Considering the putative role of Notch signaling in the maintenance of the cancer stem cells (CSC) phenotype in RELA-fused EPN, we investigated the expression of Notch pathway and its target g...read more

Mentioned in this Paper

Biological Markers
Study
Biochemical Pathway
HES4
Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester
Genes
Tumor Markers, Biological
24-diamino-5-phenylthiazole
CDK6
Inhibitors
4
1
4
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Notch pathway in ependymoma RELA-fused subgroup: upregulation and association with cancer stem cells markers expression

Cancer Gene Therapy

Jul 17, 2019

Taciani de Almeida MagalhãesKleiton Silva Borges

PMID: 31308481

DOI: 10.1038/s41417-019-0122-x

Abstract

RELA-fused supratentorial (ST) ependymoma (EPN) is an aggressive subgroup with poor prognosis. Considering the putative role of Notch signaling in the maintenance of the cancer stem cells (CSC) phenotype in RELA-fused EPN, we investigated the expression of Notch pathway and its target g...read more

Mentioned in this Paper

Biological Markers
Study
Biochemical Pathway
HES4
Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester
Genes
Tumor Markers, Biological
24-diamino-5-phenylthiazole
CDK6
Inhibitors
4
1
4

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Paper Details
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  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
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    No citations available

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