Novel [2 + 2 + 2 + 1] cycloaddition of enediynes catalyzed by rhodium complexes

Organic Letters
Bibia BennacerIwao Ojima

Abstract

[reaction: see text] The first Rh-catalyzed intramolecular [2 + 2 + 2 + 1] cycloaddition reaction of enediynes and CO is reported. This novel higher order cycloaddition process gives the corresponding 5-7-5 ring systems in high yield and selectivity. This process is another significant addition to the arsenal of cycloaddition-based synthetic methods, which provide powerful tools for rapid and efficient construction of complex polycyclic systems.

References

Feb 1, 1996·Chemical Reviews·Paul A. Wender
Mar 28, 1996·Chemical Reviews·Iwao OjimaRobert J. Donovan
Mar 14, 2002·Chemical Reviews·Corinne AubertMax Malacria
Jul 26, 2002·Journal of the American Chemical Society·Scott R Gilbertson, Brenton DeBoef

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Citations

Sep 21, 2010·Chemical Communications : Chem Comm·Wanxiang Zhao, Junliang Zhang
Apr 3, 2008·Angewandte Chemie·Véronique MicheletJean-Pierre Genêt
Feb 10, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Laura SalaczGaëlle Blond
Jul 27, 2020·Chemistry : a European Journal·Barry M TrostJohnathan E Schultz
Feb 21, 2008·The Journal of Physical Chemistry. a·M Merced Montero-CampilloEnrique Cabaleiro-Lago
Apr 20, 2021·Chemistry : a European Journal·Alberto FelicianoMiguel A Vázquez
Feb 10, 2007·The Journal of Organic Chemistry·Philip J ParsonsJohnathan Board

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