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Novel APC-like properties of human NK cells directly regulate T cell activation

bioRxiv

Mar 30, 2015

Jacob H. Hanna, Ofer Mandelboim

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Abstract

Initiation of the adaptive immune response is dependent on the priming of naive T cells by APCs. Proteomic analysis of unactivated and activated human NK cell membrane-enriched fractions demonstrated that activated NK cells can efficiently stimulate T cells, since they upregulate MHC cl...read more

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Naive T-Lymphocyte
Ligands
Tonsil
Cell Surface
NK 2 (2,4-dichlorophenoxy)acetic acid, (4-hydroxy-3-nitrophenyl)methyl ester)
Decidual
Cytomegalovirus Infections
Transcription Initiation
Natural Killer Cells
T-Cell Activation
10
1
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  • Novel APC-like properties of human NK cells directly regulate T cell activation

    bioRxiv

    Mar 30, 2015

    Jacob H. Hanna, Ofer Mandelboim

    PMID: 990016816

    DOI: 10.1101/016816

    Abstract

    Initiation of the adaptive immune response is dependent on the priming of naive T cells by APCs. Proteomic analysis of unactivated and activated human NK cell membrane-enriched fractions demonstrated that activated NK cells can efficiently stimulate T cells, since they upregulate MHC cl...read more

    Mentioned in this Paper

    Naive T-Lymphocyte
    Ligands
    Tonsil
    Cell Surface
    NK 2 (2,4-dichlorophenoxy)acetic acid, (4-hydroxy-3-nitrophenyl)methyl ester)
    10
    1

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