Novel approaches to the treatment of cachexia

Drug Discovery Today
Josep M ArgilésSílvia Busquets

Abstract

Cachexia is a complex syndrome. The main components of this pathological state are anorexia and metabolic abnormalities, such as glucose intolerance, fat depletion and muscle protein catabolism among others. The aim of the present article is to review the recent therapeutic approaches that have been designed to fight and counteract muscle wasting in different pathological states such as cancer, AIDS and chronic heart failure.

Citations

Aug 19, 2009·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Giovanni Mantovani, Clelia Madeddu
Jul 26, 2008·Current Treatment Options in Oncology·Katharine L Barford, James T D'Olimpio
Sep 17, 2013·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Andrea NicoliniAngelo Carpi
Jul 4, 2012·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·J M ArgilésS Busquets
Jun 14, 2012·Nature Communications·Sergio Di MarcoImed Eddine Gallouzi
Oct 13, 2010·Annals of Oncology : Official Journal of the European Society for Medical Oncology·I GioulbasanisD Mavroudis
Apr 14, 2009·Current Opinion in Clinical Nutrition and Metabolic Care·Alberto Miján-de-la-Torre
Aug 23, 2012·Nutrition & Metabolism·Mireia OlivanJosep M Argilés
Jan 11, 2011·Indian Journal of Palliative Care·Em Tazi, H Errihani
Jun 12, 2012·Case Reports in Medicine·Eriko Ogino-NishimuraJuichi Ito
Apr 13, 2012·EMBO Molecular Medicine·Ioannis GioulbasanisChristos N Papandreou
Feb 26, 2009·Expert Opinion on Pharmacotherapy·Antonio MacciòGiovanni Mantovani
Oct 20, 2012·Expert Opinion on Biological Therapy·Josep M Argilés, Britta Stemmler
May 19, 2009·Expert Opinion on Pharmacotherapy·Clelia MadedduGiovanni Mantovani
Jul 3, 2010·Expert Opinion on Biological Therapy·Fabio PennaPaola Costelli
Jun 18, 2015·The American Journal of the Medical Sciences·Tadashi Yoshida, Patrice Delafontaine
Feb 12, 2013·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Josep M ArgilésBritta Stemmler
Apr 9, 2011·Journal of Cachexia, Sarcopenia and Muscle·Pontus M A Siren, Matti J Siren
Aug 30, 2014·Journal of Cachexia, Sarcopenia and Muscle·Míriam ToledoJosep M Argilés
Nov 5, 2013·Clinical Biochemistry·Telma MartinsRita Ferreira
Jun 19, 2013·The International Journal of Biochemistry & Cell Biology·Tadashi YoshidaPatrice Delafontaine
Jun 3, 2011·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Ioannis GioulbasanisVassilis Georgoulias
Feb 27, 2009·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Steven P DunnOrly Vardeny
Jan 31, 2017·International Journal of Molecular Sciences·Ken HowickHarriët Schellekens
Apr 2, 2013·The Cochrane Database of Systematic Reviews·Vicente Ruiz GarciaSylvia Bort-Marti
Aug 12, 2009·Current Opinion in Supportive and Palliative Care·Clelia Madeddu, Giovanni Mantovani
Jul 29, 2017·The Biochemical Journal·Josep M ArgilésSílvia Busquets
Dec 9, 2008·Current Opinion in Supportive and Palliative Care
Nov 6, 2009·Current Opinion in Supportive and Palliative Care

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