Novel biomarkers in hepatocellular carcinoma

Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Felice De StefanoRoberto Gedaly

Abstract

Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths and the fifth most common cancer worldwide. Most of these patients are seen with advanced disease at the time of presentation. In spite of its high prevalence, there are not many therapeutic options available for patients with advanced-stage HCC. There is an urgent need for improving early detection and prognostication of patients with HCC. In addition, the development of new therapies targeting specific pathways involved in the pathogenesis of HCC should be a major goal for future research, with the objective of improving outcomes of patients with HCC. Biomarkers represent a relatively easy and noninvasive way to detect and estimate disease prognosis. In spite of the numerous efforts to find molecules as possible biomarkers, there is not a single ideal marker in HCC. Many new findings have shown promising results both in diagnosing and treating HCC. In this review, we summarized the most recent and relevant biomarkers in HCC.

Citations

Aug 23, 2019·Liver International : Official Journal of the International Association for the Study of the Liver·Peter R GalleAndrew X Zhu
Jan 16, 2020·Journal of Computer Assisted Tomography·Ahmed Abdel Khalek Abdel RazekWalaa Shabana
Nov 19, 2019·American Journal of Physiology. Gastrointestinal and Liver Physiology·Zhu ZhanHong Ren
Jul 15, 2020·Expert Review of Gastroenterology & Hepatology·Michele FinottiUmberto Cillo
Sep 17, 2019·Therapeutic Advances in Medical Oncology·Walid S AyoubShelly C Lu
Mar 12, 2020·Annals of Surgical Oncology·Xiang-Nan YuJi-Min Zhu
Sep 13, 2020·Journal of Cancer Research and Clinical Oncology·Olga Y BureninaOlga A Dontsova
Dec 31, 2020·Journal of Hepatocellular Carcinoma·Jingjing ZongYewei Zhang
Jan 12, 2021·Oxidative Medicine and Cellular Longevity·Qiuyuan YangShuguang Chen
Feb 21, 2021·Experimental and Molecular Pathology·Xuejing YangJianian Guo
Apr 20, 2021·Frontiers in Molecular Biosciences·Xiwen WuBaogang Peng
Jun 26, 2021·Pharmacology & Therapeutics·Yiming JinAndrew J Wiemer
Jul 27, 2021·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Xien YangGang Liu
Nov 17, 2021·Biomarkers in Medicine·Zhuo HanJianying Zhang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Hepatocellular

Hepatocellular Carcinoma is a malignant cancer in liver epithelial cells. Discover the latest research on Hepatocellular Carcinoma here.

Related Papers

Expert Review of Anticancer Therapy
Sameh MikhailAmer Zeidan
Hepatobiliary & Pancreatic Diseases International : HBPD INT
Wan-Yee Lau, Eric C H Lai
Therapeutische Umschau. Revue thérapeutique
David Semela, Markus Heim
© 2022 Meta ULC. All rights reserved