PMID: 6406910Jun 23, 1983Paper

Novel clonal strains from adult rat anterior pituitary producing S-100 protein

Nature
H IshikawaN Shirasawa

Abstract

S-100 protein, one of the unique proteins found in the nervous system, has recently been discovered unexpectedly in the rat anterior pituitary. Immunocytochemistry reveals that stellate, follicular and folliculostellate cells, and marginal cells of the rat anterior pituitary contain this protein; however, as far as we know, there are no reports on the physiological role of this protein in the anterior pituitary. In the study reported here, three S-100 protein-producing clonal strains (JH-S3, JH-S8 and JH-S12) from adult rat anterior pituitaries were established by using the single cell-plating feeder layer method. These new clonal strains reveal that the S-100 protein-producing cell is an independent cell type of the anterior pituitary. Both cultures and grafts of the JH-S3 cells stain immunocytochemically with anti-S100 protein IgG fraction. Moreover, the S-100 protein and conditioned medium of JH-S3 clonal cells both stimulate release of prolactin from prolactin-secreting clonal cells (1G4) in vitro.

References

May 31, 1978·Anatomy and Embryology·P H Frémont, R Ferrand
Sep 1, 1977·Proceedings of the Society for Experimental Biology and Medicine·H IshikawaE G Rennels
May 1, 1972·Journal of Neurochemistry·N MianiA Caniglia
Jan 1, 1972·International Review of Neurobiology·B W Moore
Jun 9, 1965·Biochemical and Biophysical Research Communications·B W Moore
May 7, 1971·Biochemical and Biophysical Research Communications·P Calissano, A D Bangham
Jan 1, 1972·Zeitschrift für Zellforschung und mikroskopische Anatomie·K P Dingemans, C A Feltkamp
Dec 1, 1969·The American Journal of Anatomy·J Schechter
Jun 9, 1980·Brain Research·T NakajimaK Takahashi
Mar 1, 1980·Journal of the Neurological Sciences·H HydénS Larsson
Jan 1, 1964·The American Journal of Anatomy·E G RENNELS
Jan 1, 1948·Acta Pathologica Et Microbiologica Scandinavica·O OUCHTERLONY

❮ Previous
Next ❯

Citations

Jan 1, 1987·Virchows Archiv. A, Pathological Anatomy and Histopathology·G E PfyfferC W Heizmann
Jan 1, 1987·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·D BenEzra, C C Chan
Nov 23, 2006·International Journal of Legal Medicine·Takaki IshikawaHitoshi Maeda
Dec 15, 1987·Brain Research·L J Van Eldik, D B Zimmer
Nov 10, 1992·Biochimica Et Biophysica Acta·S W BargerL J Van Eldik
Sep 5, 1996·Brain Research. Molecular Brain Research·A R PortaF L Margolis
May 1, 1995·Progress in Neurobiology·G FanòP Calissano
Jun 18, 1990·Molecular and Cellular Endocrinology·W AllaertsC Denef
Nov 1, 1988·Trends in Biochemical Sciences·D Kligman, D C Hilt
Oct 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·D Kligman, D R Marshak
Jul 23, 2011·Neuroendocrinology·Sandrine M Dupré
Jul 5, 2005·European Journal of Endocrinology·Wilfried Allaerts, Hugo Vankelecom
Apr 1, 1990·Journal of Neurochemistry·K KatoT Sato
Oct 1, 1990·Journal of Neurochemistry·Y Mely, D Gérard
Jan 1, 1984·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·L LauriolaF Michetti
Jan 1, 1985·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·L LauriolaD Cocchia
Oct 31, 1986·Biochimica Et Biophysica Acta·F Suzuki, K Kato
Nov 16, 2004·Molecular and Cellular Endocrinology·Guck T OoiRuth M Escalona
Nov 1, 1984·Journal of Neurochemistry·F SuzukiT Nakajima
Apr 1, 1989·The Anatomical Record·S KamiyaM Daigo
May 1, 1988·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·F Harrisson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.