Novel coronavirus epidemic in the Hungarian population, a cross-sectional nationwide survey to support the exit policy in Hungary

GeroScience
Béla MerkelyHUNgarian COronaVirus-19 Epidemiological Research (H-UNCOVER) investigators

Abstract

After months of restrictive containment efforts to fight the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) epidemic, European countries are planning to reopen. To support the process, we conducted a cross-sectional survey among the Hungarian population to estimate the prevalence of infectious cases and prior SARS-CoV-2 exposure. A representative sample (n = 17,787) for the Hungarian population of 14 years or older living in private households (n = 8,283,810) was selected. The study was performed within 16 days after 50 days of restrictions, when the number of confirmed cases was stable low. Naso- and oropharyngeal smears and blood samples were collected for PCR and antibody testing. The testing was accompanied by a questionnaire about symptoms, comorbidities, and contacts. Design-based prevalence estimates were calculated. In total, 10,474 individuals (67.7% taken into account a sample frame error of 2315) of the selected sample participated in the survey. Of the tested individuals, 3 had positive PCR and 69 had positive serological test. Population estimate of the number of SARS-CoV-2 infection and seropositivity were 2421 and 56,439, respectively, thus active infection rate (2.9/10,000) and the prevalence of pr...Continue Reading

Associated Clinical Trials

References

Sep 2, 1995·BMJ : British Medical Journal·E EypaschH Troidl
Feb 20, 2020·The New England Journal of Medicine·Marc LipsitchLyn Finelli
Feb 29, 2020·The New England Journal of Medicine·Wei-Jie GuanUNKNOWN China Medical Treatment Expert Group for Covid-19
Mar 24, 2020·JAMA : the Journal of the American Medical Association·Graziano OnderSilvio Brusaferro
Apr 7, 2020·JAMA : the Journal of the American Medical Association·Giacomo GrasselliUNKNOWN COVID-19 Lombardy ICU Network
Apr 15, 2020·The New England Journal of Medicine·Daniel F GudbjartssonKari Stefansson
Apr 23, 2020·JAMA : the Journal of the American Medical Association·Giacomo SpinatoPaolo Boscolo-Rizzo
May 4, 2020·Lancet·Nigel CurtisMihai G Netea
May 16, 2020·Gut·Elisabetta BuscariniGiuseppe Lauria
Mar 27, 2020·MedRxiv : the Preprint Server for Health Sciences·J. ZhaoPeng George Wang
Jun 5, 2020·MedRxiv : the Preprint Server for Health Sciences·G. RöstB. Oroszi

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Citations

Aug 19, 2020·GeroScience·Akshay Swaminathan, S V Subramanian
Oct 14, 2020·Current Allergy and Asthma Reports·Khang Wen PangChew Lip Ng
Oct 30, 2020·The Journal of Infectious Diseases·Edward GoldsteinMuge Cevik
Nov 6, 2020·BMJ : British Medical Journal·Kata Karáth
Mar 16, 2021·Bulletin of the World Health Organization·John P A Ioannidis
May 25, 2021·Brain, Behavior, & Immunity Health·A BoscuttiP Brambilla
Jun 27, 2021·Proceedings of the National Academy of Sciences of the United States of America·David KlineSamuel J Clark
Jul 15, 2021·Reviews in Medical Virology·Vinícius Bonetti FranceschiClaudia Elizabeth Thompson
Aug 23, 2021·European Journal of Epidemiology·Laura EspenhainSteen Ethelberg

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Methods Mentioned

BETA
PCR

Software Mentioned

UNCOVER
SAS

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