Novel drug metabolites produced by functionalization reactions: chemistry and toxicology

Drug Metabolism Reviews
Bernard Testa, P Jenner

Abstract

No abstract listed.

References

Feb 1, 1976·Toxicology and Applied Pharmacology·T C Campbell, J R Hayes
Jan 1, 1976·The Journal of Pharmacy and Pharmacology·P Hodges
Sep 1, 1976·The Journal of Pharmacy and Pharmacology·A H Beckett, P M Bélanger
Aug 1, 1976·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·L L PoulsenD M Ziegler
Aug 1, 1976·The Journal of Pharmacy and Pharmacology·A Frigerio, C Pantarotto
Jan 1, 1977·The Journal of Pharmacy and Pharmacology·A H BeckettP H Morgan
Apr 1, 1977·The Journal of Pharmacy and Pharmacology·A H Beckett, R Achari
Feb 1, 1977·Clinical Pharmacology and Therapeutics·J KapitulnikA H Conney
Jan 1, 1975·The Journal of Pharmacy and Pharmacology·A A SmithM Crofford
Jul 1, 1975·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·G R KeysellP Sims
Jan 1, 1978·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·P Jenner, Bernard Testa
Feb 1, 1977·Biochemical Pharmacology·G J MulderJ R Gillette
Apr 1, 1976·Chemico-biological Interactions·J V Frei
Jul 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·J J Wong, D P Hsieh
Jan 1, 1976·Mutation Research·B M Cattanach
Jan 1, 1976·Drug Metabolism Reviews·A FrigerioG Belvedere
Feb 1, 1975·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·D E CaseP Simons
Dec 15, 1975·Biochemical Pharmacology·J CaldwellR T Williams
Aug 1, 1976·Journal of Medicinal Chemistry·R A Lahti, M Gall
Jan 5, 1977·Journal of the American Chemical Society·K NakanishiI B Weinstein
Jan 1, 1977·Toxicology and Applied Pharmacology·W H Braun, J D Young
Apr 1, 1977·Biochemical Pharmacology·G M Rosen, E Rauchman
Sep 15, 1976·Journal of the American Chemical Society·D M JerinaD T Gibson
Sep 15, 1976·Journal of the American Chemical Society·Y HataA Touchi
Dec 1, 1976·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·J G PageS L Due
Jan 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·W LevinA H Conney
Oct 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·D R ThakkerA H Conney
Jan 1, 1975·Biochemical Society Transactions·P Sims
Jan 1, 1975·Biochemical Society Transactions·J C PhillipsA G Lloyd
Jul 11, 1975·Journal of Medicinal Chemistry·J GalN Castagnoli
Oct 1, 1975·Archives of Biochemistry and Biophysics·T HayakawaD M Jerina
Sep 1, 1975·Biochemical Pharmacology·C Y WangG T Bryan
Jan 1, 1975·Biochemical Society Transactions·J R Mitchell
Apr 14, 1976·Journal of the American Chemical Society·J W Keller, C Heidelberger
May 26, 1976·Journal of the American Chemical Society·M S NewmanD R Olson
Apr 1, 1973·The Journal of Pharmacy and Pharmacology·A H Beckett, S al-Sarraj
May 1, 1974·Archives of Biochemistry and Biophysics·F F Kadlubar, D M Ziegler
May 1, 1974·The Journal of Pharmacy and Pharmacology·A H BeckettF A Ogunbona
Jul 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·H W Orf, D Dolphin
Dec 1, 1969·The Journal of Pharmacy and Pharmacology·D KraussU Breyer
Nov 1, 1972·The Journal of Pharmacy and Pharmacology·A H Beckett, S al-Sarraj
May 1, 1974·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·A H Beckett, K K Midha
Aug 1, 1974·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·A H Beckett, P M Bélanger
Oct 11, 1974·Nature·J R MitchellD J Jollow
Oct 8, 1974·Biochemical and Biophysical Research Communications·D H SwensonJ A Miller
Dec 15, 1974·Biochemical Pharmacology·L L PoulsenD M Ziegler
Oct 1, 1974·Archives of Biochemistry and Biophysics·L L PoulsenD M Ziegler
Feb 1, 1973·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·J E PittsJ B Forehand
May 1, 1973·Journal of Medicinal Chemistry·I C CalderJ D Tange
Oct 1, 1973·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·P J Meffin, J Thomas
May 1, 1972·Archives of Biochemistry and Biophysics·D M Ziegler, C H Mitchell
Jul 1, 1971·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·A H Beckett

Citations

Sep 1, 1980·Journal of Toxicology and Environmental Health·O Pelkonen, K Vähäkangas
Sep 30, 2003·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·I D Wilson, J K Nicholson
Jan 1, 1981·Drug Metabolism Reviews·Bernard Testa, P Jenner
Jan 1, 1979·Drug Metabolism Reviews·K C Leibman
Jan 1, 1982·Drug Metabolism Reviews·B Lindeke
Jan 1, 1983·Drug Metabolism Reviews·P G Dayton, J E Sanders
Feb 7, 2012·Drug Discovery Today·Bernard TestaGiulio Vistoli
Dec 29, 2006·Chemistry & Biodiversity·Bernard Testa, Stefanie D Krämer
Aug 1, 1986·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·K SudoH Tachizawa
Feb 1, 1986·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·T InoueT Niwaguchi
Jan 1, 1979·European Journal of Drug Metabolism and Pharmacokinetics·K J HoffmannK O Borg
Jan 1, 1983·Critical Reviews in Toxicology·T L Macdonald
Jan 1, 1990·Acta Psychiatrica Scandinavica. Supplementum·R JauchT W Guentert

Related Concepts

Amines
Aziridines
Cyclization
Dealkylation
Pharmaceutical Preparations
Heterocyclic Compounds
Hydrazines
Oxidation-Reduction
Polycyclic Hydrocarbons

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Lipidomics & Rhinovirus Infection

Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Torsion Dystonia

Torsion dystonia is a movement disorder characterized by loss of control of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. Here is the latest research.

Generating Insulin-Secreting Cells

Reprogramming cells or using induced pluripotent stem cells to generate insulin-secreting cells has significant therapeutic implications for diabetics. Here is the latest research on generation of insulin-secreting cells.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Epigenome Editing

Epigenome editing is the directed modification of epigenetic marks on chromatin at specified loci. This tool has many applications in research as well as in the clinic. Find the latest research on epigenome editing here.