Novel imaging approaches for small animal models of lung disease (2017 Grover Conference series)

Pulmonary Circulation
Isaac P Pinar, Heather D Jones

Abstract

Imaging in small animal models of lung disease is challenging, as existing technologies are limited either by resolution or by the terminal nature of the imaging approach. Here, we describe the current state of small animal lung imaging, the technological advances of laboratory-sourced phase contrast X-ray imaging, and the application of this novel technology and its attendant image analysis techniques to the in vivo imaging of the large airways and pulmonary vasculature in murine models of lung health and disease.

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Citations

Nov 10, 2020·Annals of the New York Academy of Sciences·Alexa MurrayDebra L Laskin
Mar 3, 2021·Scientific Reports·Michael Gerhard KaulKersten Peldschus
Sep 18, 2021·Cardiovascular Engineering and Technology·Andreas KaeslerJohanna Charlotte Clauser

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Methods Mentioned

BETA
bronchoalveolar lavage
imaging techniques
transgenic
light scattering
bioluminescence
X-ray

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