The 21st century offers new advances in diagnostic procedures and protocols in the management of esophageal diseases. This review highlights the most recent advances in esophageal diagnostic technologies, including clinical applications of novel endoscopic devices, such as ultrathin endoscopy and confocal laser endomicroscopy for diagnosis and management of Barrett's esophagus; novel parameters and protocols in high-resolution esophageal manometry for the identification and better classification of motility abnormalities; innovative connections between esophageal motility disorder diagnosis and detection of gastroesophageal reflux disease (GERD); impedance-pH testing for detecting the various GERD phenotypes; performance of distensibility testing for better pathophysiological knowledge of the esophagus and other gastrointestinal abnormalities; and a modern view of positron emission tomography scanning in metastatic disease detection in the era of accountability as a model for examining other new technologies. We now have better tools than ever for the detection of esophageal diseases and disorders, and emerging data are helping to define how well these tools change management and provide value to clinicians. This review feature...Continue Reading
Multichannel intraluminal impedance in esophageal function testing and gastroesophageal reflux monitoring
Clarification of the esophageal function defect in patients with manometric ineffective esophageal motility: studies using combined impedance-manometry
Systematic review of the staging performance of 18F-fluorodeoxyglucose positron emission tomography in esophageal cancer
Combined multichannel intraluminal impedance and pH-metry: a novel technique to improve detection of gastro-oesophageal reflux literature review
Feasibility and safety of string, wireless capsule endoscopy in the diagnosis of Barrett's esophagus
Platelet-activating factor and prostaglandin E2 impair esophageal ACh release in experimental esophagitis
A new technique for evaluating sphincter function in visceral organs: application of the functional lumen imaging probe (FLIP) for the evaluation of the oesophago-gastric junction
Addition of esophageal impedance monitoring to pH monitoring increases the yield of symptom association analysis in patients off PPI therapy
Esophageal pH-impedance monitoring and symptom analysis in GERD: a study in patients off and on therapy
The utility of positron emission tomography in staging of potentially operable carcinoma of the thoracic esophagus: results of the American College of Surgeons Oncology Group Z0060 trial
Impedance manometry with viscous test solution increases detection of esophageal function defects compared to liquid swallows
Clinical trial: persistent gastro-oesophageal reflux symptoms despite standard therapy with proton pump inhibitors - a follow-up study of intraluminal-impedance guided therapy
Physiology of the oesophageal transition zone in the presence of chronic bolus retention: studies using concurrent high resolution manometry and digital fluoroscopy
Total fundoplication controls acid and nonacid reflux: evaluation by pre- and postoperative 24-h pH-multichannel intraluminal impedance.
Prospective assessment of patient selection for antireflux surgery by combined multichannel intraluminal impedance pH monitoring.
The role of nonacid reflux in NERD: lessons learned from impedance-pH monitoring in 150 patients off therapy
Stepwise radiofrequency ablation of Barrett's esophagus preserves esophageal inner diameter, compliance, and motility
Systematic review of narrow-band imaging for the detection and differentiation of abnormalities in the esophagus and stomach (with video)
High-resolution manometry in clinical practice: utilizing pressure topography to classify oesophageal motility abnormalities.
Functional heartburn has more in common with functional dyspepsia than with non-erosive reflux disease.
Reflux patterns in patients with short-segment Barrett's oesophagus: a study using impedance-pH monitoring off and on proton pump inhibitor therapy
Esophagogastric junction distensibility after fundoplication assessed with a novel functional luminal imaging probe.
Characteristics of reflux episodes and symptom association in patients with erosive esophagitis and nonerosive reflux disease: study using combined impedance-pH off therapy
Indications and detection, completion, and retention rates of small-bowel capsule endoscopy: a systematic review
Esophagogastric junction distensibility assessed with an endoscopic functional luminal imaging probe (EndoFLIP).
Characteristics of gastro-esophageal reflux episodes in Barrett's esophagus, erosive esophagitis and healthy volunteers
Reflux parameters as modified by laparoscopic fundoplication in 40 patients with heartburn/regurgitation persisting despite PPI therapy: a study using impedance-pH monitoring.
Acceptability and accuracy of a non-endoscopic screening test for Barrett's oesophagus in primary care: cohort study.
Barrett’s esophagus if a serious complication of gastroesophageal reflux disease during which the normal esophageal lining changes to tissue that resembles intestinal lining. Here is the latest research.