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Novel insights into RNAi off-target effects using C. elegans paralogs

BMC Genomics

Apr 21, 2007

Jean-François RualGuillaume Achaz

Abstract

In the few years since its discovery, RNAi has turned into a very powerful tool for the study of gene function by allowing post-transcriptional gene silencing. The RNAi mechanism, which is based on the introduction of a double-stranded RNA (dsRNA) trigger whose sequence is similar to th...read more

Mentioned in this Paper

Calcinus elegans
Cyartonema elegans
Coleonyx elegans
Biochemical Pathway
Cestrum elegans
Clarkia unguiculata
Clathrulina elegans
Cardioglossa elegans
Cymbella elegans
Cyrenella elegans
Paper Details
References
  • References31
  • Citations22
123

Novel insights into RNAi off-target effects using C. elegans paralogs

BMC Genomics

Apr 21, 2007

Jean-François RualGuillaume Achaz

PMID: 17445269

DOI: 10.1186/1471-2164-8-106

Abstract

In the few years since its discovery, RNAi has turned into a very powerful tool for the study of gene function by allowing post-transcriptional gene silencing. The RNAi mechanism, which is based on the introduction of a double-stranded RNA (dsRNA) trigger whose sequence is similar to th...read more

Mentioned in this Paper

Calcinus elegans
Cyartonema elegans
Coleonyx elegans
Biochemical Pathway
Cestrum elegans
Clarkia unguiculata
Clathrulina elegans
Cardioglossa elegans
Cymbella elegans
Cyrenella elegans

Related Papers

Paper Details
References
  • References31
  • Citations22
123
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