Novel lead for potent inhibitors of breast cancer resistance protein (BCRP)

Bioorganic & Medicinal Chemistry Letters
Anne PickMichael Wiese

Abstract

From our modulator library an interesting inhibitor of breast cancer resistance protein (BCRP) was identified. Due to its high inhibitory potency, this compound may serve as a promising novel lead for the design of new and potent modulators. This adds a new structural class to the few known highly active BCRP inhibitors.

Citations

Dec 15, 2011·Journal of Medicinal Chemistry·Glaucio ValdameriAttilio Di Pietro
Mar 5, 2016·Journal of Medicinal Chemistry·Sven Marcel SchmittMichael Wiese
Dec 23, 2016·Medicinal Research Reviews·Diana Peña-SolórzanoCristian Ochoa-Puentes
May 1, 2014·Molecular Informatics·Floriane Montanari, Gerhard F Ecker
Mar 5, 2015·ChemMedChem·Federico MarighettiMichael Wiese
Apr 10, 2015·Journal of Medicinal Chemistry·Sebastian C Köhler, Michael Wiese

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.