Novel micro RNA-based therapies for the treatment of neuroblastoma

Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)
Ariadna BoloixMiguel F Segura

Abstract

Neuroblastoma (NB) is the most common solid tumour in children and adolescents, and accounts for up to 15% of all cancer deaths in this group. It originates in the sympathetic nervous system, and its behaviour can be very aggressive and become resistant to current treatments. A review is presented, summarising the new alternative therapies based on epigenetics, i.e., modulators of gene expression, such as microRNAs and their potential application in the clinical practice of NB treatment.

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Citations

Feb 17, 2019·Cellular and Molecular Life Sciences : CMLS·Aroa SorianoMiguel F Segura

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