Novel nitrofurazone derivatives endowed with antimicrobial activity

Archiv der Pharmazie
Dalci J BrondaniAna C L Leite

Abstract

The N-alkylated derivatives from nitrofurazone were synthesised and evaluated in vitro for their efficacy as antimicrobial agents against representative strains, including methicillin-resistant Staphylococcus aureus (MRSA). The derivative 2a demonstrated greater activity than the prototype and was comparable to currently used antimicrobial drugs.

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Citations

Nov 4, 2020·Drug Development Research·Christina KannigaduDavid D N'Da
Feb 12, 2020·Bioorganic Chemistry·Nonkululeko H ZumaDavid D N'Da

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