Novel non-peptide ligands for the somatostatin sst3 receptor

Bioorganic & Medicinal Chemistry Letters
C MoinetC Thurieau

Abstract

A series of imidazole derivatives has been prepared using high throughput parallel synthesis. Several compounds showed high affinity (Ki in 10(-6)-10(-8) M range) and selectivity at recombinant human somatostatin receptor subtype 3 (hsst3).

References

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Citations

May 28, 2002·Journal of Endocrinological Investigation·R Deghenghi
Oct 2, 2002·Clinical Endocrinology·N García de la TorreH E Turner
Aug 25, 2001·Journal of Medicinal Chemistry·L PoitoutC Thurieau
Sep 26, 2003·Biochimica Et Biophysica Acta·Lars Neisig MøllerJens Juul Holst

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