Novel optimum contribution selection methods accounting for conflicting objectives in breeding programs for livestock breeds with historical migration

Genetics, Selection, Evolution : GSE
Yu WangR Wellmann

Abstract

Optimum contribution selection (OCS) is effective for increasing genetic gain, controlling the rate of inbreeding and enables maintenance of genetic diversity. However, this diversity may be caused by high migrant contributions (MC) in the population due to introgression of genetic material from other breeds, which can threaten the conservation of small local populations. Therefore, breeding objectives should not only focus on increasing genetic gains but also on maintaining genetic originality and diversity of native alleles. This study aimed at investigating whether OCS was improved by including MC and modified kinships that account for breed origin of alleles. Three objective functions were considered for minimizing kinship, minimizing MC and maximizing genetic gain in the offspring generation, and we investigated their effects on German Angler and Vorderwald cattle. In most scenarios, the results were similar for Angler and Vorderwald cattle. A significant positive correlation between MC and estimated breeding values of the selection candidates was observed for both breeds, thus traditional OCS would increase MC. Optimization was performed under the condition that the rate of inbreeding did not exceed 1% and at least 30% of...Continue Reading

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Citations

Jul 13, 2019·Animal : an International Journal of Animal Bioscience·S KohlP Herold
May 23, 2019·Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie·Yu WangRobin Wellmann
Jun 20, 2019·Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie·Jonas SchälerGeorg Thaller
Sep 3, 2019·Frontiers in Genetics·Robin Wellmann, Jörn Bennewitz
Mar 3, 2019·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Joshua N CobbEng Hwa Ng
Mar 8, 2021·Genetics, Selection, Evolution : GSE·Christin SchmidtmannGeorg Thaller
Aug 28, 2021·Animals : an Open Access Journal From MDPI·Antonio González ArizaMaría Esperanza Camacho Vallejo

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Software Mentioned

R package optiSel
optiSel
CVXOPT
R package
Solver “ cccp

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