Novel pharmaceutical options for treating fibromyalgia

Expert Review of Clinical Pharmacology
Maria Chiara GerardiPiercarlo Sarzi-Puttini

Abstract

Fibromyalgia is a chronic disorder whose symptoms have a devastating effect on patients' lives as they limit their ability to engage in everyday working and social activities, and make it difficult to maintain normal relationships with family, friends and employers. None of the currently available drugs are fully effective against the whole spectrum of symptoms of pain, fatigue, sleep disturbances and depression, but increasing efforts by the pharmaceutical industry have led to the introduction of new investigational drugs and new formulations of older drugs, as well as studies of the possibility of applying drugs currently used for other diseases. The aim of this review is to summarise the data relating to the new therapeutic options that have become available over the last few years.

References

Jan 1, 1995·Arthritis and Rheumatism·F WolfeL Hebert
Nov 26, 1998·Clinical Endocrinology·J WiknerS Röjdmark
Apr 7, 2000·Clinical Rheumatology·G CiteraD P Cardinalli
Aug 30, 2003·Current Pain and Headache Reports·Mollie E Thompson, André Barkhuizen
Feb 12, 2004·Arthritis and Rheumatism·Jeanne K TofferiPatrick G O'Malley
Feb 4, 2006·Current Pharmaceutical Design·Daniel J Wallace
Mar 14, 2007·Seminars in Arthritis and Rheumatism·Muhammad B Yunus
May 17, 2007·Current Pain and Headache Reports·Dane B CookMichael J McLoughlin
Jul 24, 2007·Annals of the Rheumatic Diseases·S F CarvilleUNKNOWN EULAR
Nov 3, 2007·The Journal of Pain : Official Journal of the American Pain Society·Ryan Quinlan SkrabekDaryl Perry
Nov 1, 2008·Current Pain and Headache Reports·Philip J Mease, Kristin Seymour
Dec 17, 2009·Anesthesia and Analgesia·Mark A WareYoram Shir
Sep 14, 2010·BMC Musculoskeletal Disorders·Piedad Morillas-ArquesElena P Calandre
Dec 17, 2010·Journal of Pineal Research·Saad Abdul-Rehman HussainFaiq Isho Gorial
May 18, 2011·BMC Musculoskeletal Disorders·Elena P CalandreFernando Rico-Villademoros
Nov 19, 2011·Best Practice & Research. Clinical Rheumatology·Roland Staud
Nov 19, 2011·Best Practice & Research. Clinical Rheumatology·Philip J MeasePiercarlo Sarzi-Puttini
May 9, 2012·Mayo Clinic Proceedings·Lesley M ArnoldUNKNOWN FibroCollaborative
Jul 5, 2012·Der Schmerz·C SommerUNKNOWN Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften
Jul 19, 2012·Current Rheumatology Reports·Elena Pita CalandreCarmen María Rodríguez-López
Jul 31, 2012·Rheumatology International·Benigno CasanuevaMiguel A González-Gay
Mar 12, 2013·Brain : a Journal of Neurology·Nurcan ÜçeylerClaudia Sommer
Jun 12, 2013·Pain Research & Management : the Journal of the Canadian Pain Society = Journal De La Société Canadienne Pour Le Traitement De La Douleur·Mary-Ann FitzcharlesUNKNOWN National Fibromyalgia Guideline Advisory Panel
Feb 11, 2014·Rheumatology International·S MameliR Agabio
Apr 11, 2014·Arthritis & Rheumatology·P Sarzi-Puttini, F Atzeni
May 24, 2014·Neuron·Brittany D WrightMark J Zylka
Oct 7, 2014·Cellular and Molecular Neurobiology·Toshizo IshikawaHironori Sasaki

❮ Previous
Next ❯

Citations

Dec 9, 2016·Expert Review of Pharmacoeconomics & Outcomes Research·Tracy L Skaer, Winghan Jacqueline Kwong
Feb 20, 2018·The Cochrane Database of Systematic Reviews·Joelle ThorpeIan Gilron
Jul 14, 2020·International Journal of Psychiatry in Clinical Practice·Omar S GammohHrayr Attarian
Jan 16, 2021·Journal of Psychiatric and Mental Health Nursing·Ahmed Mohammad Al-SmadiHrayr Attarian

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.