Novel SF3B1 in-frame deletions result in aberrant RNA splicing in CLL patients

Blood Advances
Anant A AgrawalSilvia Buonamici

Abstract

We identify and characterize novel SF3B1 in-frame deletions in chronic lymphocytic leukemia.These deletions are functionally similar to well-known SF3B1 hotspot mutations and are sensitive to splicing modulation.

References

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