Novel techniques for enhancing sensitivity in static headspace extraction-gas chromatography

Journal of Chromatography. a
N H Snow, G P Bullock

Abstract

Static headspace extraction-gas chromatography (SHE-GC) is one of the most commonly used techniques for the analysis of volatile compounds. It is considered by most to be a mature technique and to an extent this is true: there are many users from outside the traditional chromatography research community developing and publishing SHE-GC methods and there are numerous instruments and devices for SHE-GC commercially available. However, research on new SHE-GC methods continues. In this review, several interesting new developments in SHE-GC are described using examples from the past three years' literature. First, the fundamental theory of SHE-GC is reviewed to provide a basis and common theme for the discussion of new methods. Next, several areas of SHE-GC research are explored: new sampling configurations, analyte derivatization and ionic liquids as solvents. These are all means for enhancing partitioning of the analyte into the vapor phase, thus improving analytical sensitivity of the overall SHE-GC method. Ideally, partitioning of analytes into the vapor phase is increased while partitioning of matrix components is not, or is decreased. There are many aspects of the seemingly straightforward process in SHE-GC that require furthe...Continue Reading

References

Nov 4, 2006·Journal of Biochemical and Biophysical Methods·Minna Hakkarainen
Dec 25, 2007·Journal of Chromatography. a·Eunha Hoh, Katerina Mastovska

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Citations

Jan 10, 2012·Journal of Agricultural and Food Chemistry·Maria Jose Cardador, Mercedes Gallego
May 10, 2011·Journal of Pharmaceutical and Biomedical Analysis·Ward D'AutryAnn Van Schepdael
Dec 23, 2015·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·René Holm, David P Elder
Aug 15, 2015·Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes·Marek MiszczykKlaudia Pszczolińska
Oct 19, 2016·Journal of Separation Science·Kaelyn GrasRobert A Shellie
Feb 21, 2018·The Analyst·H Kočová VlčkováL Nováková
Oct 6, 2018·Journal of Separation Science·Adissu Alemayehu AsfawErwin Adams
Mar 15, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Christopher FinneganGuiomar Garcia-Cabellos
Mar 21, 2021·Journal of Chromatography. a·Colin F Poole, Sanka N Atapattu
May 28, 2010·Analytical Chemistry·Frank L DormanJorge Gardea-Torresdey

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