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Novo&Stitch: accurate reconciliation of genome assemblies via optical maps

Bioinformatics

Jul 1, 2018

Wei-hua PanStefano Lonardi

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Abstract

De novo genome assembly is a challenging computational problem due to the high repetitive content of eukaryotic genomes and the imperfections of sequencing technologies (i.e. sequencing errors, uneven sequencing coverage and chimeric reads). Several assembly tools are currently availabl...read more

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Genome
Molecular Assembly/Self Assembly
Mullerian duct inhibiting substance
Nucleic Acid Sequencing
Chimera Organism
Asthenia
Genome Mapping
Medication Reconciliation
Novo Nordisk
Sequencing
10
21
Paper Details
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Novo&Stitch: accurate reconciliation of genome assemblies via optical maps

Bioinformatics

Jul 1, 2018

Wei-hua PanStefano Lonardi

PMID: 29949964

DOI: 10.1093/bioinformatics/bty255

Abstract

De novo genome assembly is a challenging computational problem due to the high repetitive content of eukaryotic genomes and the imperfections of sequencing technologies (i.e. sequencing errors, uneven sequencing coverage and chimeric reads). Several assembly tools are currently availabl...read more

Mentioned in this Paper

Genome
Molecular Assembly/Self Assembly
Mullerian duct inhibiting substance
Nucleic Acid Sequencing
Chimera Organism
10
21
Paper Details
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