Abstract
Zika virus (ZIKV) was recognised as a zoonotic pathogen in Africa and southeastern Asia. Human infections were infrequently reported until 2007, when the first known epidemic occurred in Micronesia. After 2013, the Asian lineage of ZIKV spread along the Pacific Islands and Americas, causing severe outbreaks with millions of human infections. The recent human infections of ZIKV were also associated with severe complications, such as an increase in cases of Guillain-Barre syndrome and the emergence of congenital Zika syndrome. To better understand the recent and rapid expansion of ZIKV, as well as the presentation of novel complications, we compared the genetic differences between the African sylvatic lineage and the Asian epidemic lineage that caused the recent massive outbreaks. The epidemic lineages have significant codon adaptation in NS1 gene to translate these proteins in human and Aedes aegypti mosquito cells compared to the African zoonotic lineage. Accordingly, a Brazilian epidemic isolate (ZBR) produced more NS1 protein than the MR766 African lineage (ZAF) did, as indicated by proteomic data from infections of neuron progenitor cells-derived neurospheres. Although ZBR replicated more efficiently in these cells, the diff...Continue Reading
References
Jul 15, 1977·Virology·E G Westaway
Mar 1, 1990·Gene·F Wright
Feb 11, 1987·Nucleic Acids Research·P M Sharp, W H Li
Jan 1, 1984·Virus Research·E G WestawayL Endo
May 9, 2001·Journal of Molecular Evolution·G M JenkinsE C Holmes
Dec 31, 2003·Advances in Virus Research·Brett D Lindenbach, Charles M Rice
Oct 29, 2004·Bioinformatics·Sergei L Kosakovsky PondSpencer V Muse
Feb 28, 2006·Journal of Virology·Dianna EdgilEva Harris
Nov 26, 2008·Nature Biotechnology·Jürgen Cox, Matthias Mann
Oct 1, 2009·Emerging Infectious Diseases·Edward B Hayes
Nov 6, 2009·Molecular Systems Biology·Iris BahirMichal Linial
Dec 4, 2010·Nature Protocols·Giuseppe PalmisanoMartin R Larsen
Mar 1, 2012·Molecular Biology and Evolution·Alexei J DrummondAndrew Rambaut
Mar 26, 2013·Antiviral Research·David A Muller, Paul R Young
Jul 3, 2013·Trends in Genetics : TIG·Eli Eisenberg, Erez Y Levanon
Jan 1, 2014·Viruses·Margo A Brinton
Jan 15, 2014·PLoS Neglected Tropical Diseases·Oumar FayeAmadou Alpha Sall
Jul 9, 2014·Médecine et maladies infectieuses·S IoosM Herida
Nov 7, 2014·PLoS Pathogens·Ben LongdonFrancis M Jiggins
Jul 22, 2015·Lancet·Didier MussoDuane J Gubler
Nov 4, 2015·BMC Infectious Diseases·Cheikh Tidiane DiagneMawlouth Diallo
Mar 5, 2016·PLoS Neglected Tropical Diseases·Thais Chouin-CarneiroAnna-Bella Failloux
Mar 8, 2016·Lancet·Van-Mai Cao-LormeauFrédéric Ghawché
Mar 11, 2016·PLoS Genetics·Gerrit Brandis, Diarmaid Hughes
Jun 10, 2016·Nature·Fernanda R CugolaPatricia C B Beltrão-Braga
Jul 28, 2016·Virus Research·Juan CristinaHéctor Musto
Aug 20, 2016·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Luisa BarzonGiorgio Palù
Apr 27, 2017·Memórias do Instituto Oswaldo Cruz·Cristina PossasAkira Homma
Citations
Apr 1, 2020·Viruses·Chutchai PiewbangSomporn Techangamsuwan
Jun 8, 2018·Frontiers in Microbiology·Hong-Wai ThamMiaw-Fang Chew
Sep 27, 2019·Frontiers in Microbiology·Carolina Quintero-GilJulian Ruiz-Saenz
Oct 31, 2019·BMC Genomics·Sarra BahaJihong Meng
Nov 19, 2020·Viruses·Martin FayeOumar Faye