Nth-order linear algorithm for diffuse correlation tomography

Biomedical Optics Express
Xiaojuan ZhangYu Shang

Abstract

The current approaches to imaging the tissue blood flow index (BFI) from diffuse correlation tomography (DCT) data are either an analytical solution or a finite element method, both of which are unable to simultaneously account for the tissue heterogeneity and fully utilize the DCT data. In this study, a new imaging concept for DCT, namely NL-DCT, was created by us in which the medical images are combined with light Monte Carlo simulation to provide geometrical and heterogeneous information in tissue. Moreover, the DCT data at multiple delay time are fully utilized via iterative linear regression. The unique merit of NL-DCT in utilizing the medical images as prior information, when combined with a split Bregman algorithm for total variation minimization (Bregman-TV), was validated on a realistic human head model. Computer simulation outcomes demonstrate the accuracy and robustness of NL-DCT in localizing and separating the flow anomalies as well as the capability to preserve edges of anomalies.

References

Jul 1, 1995·Computer Methods and Programs in Biomedicine·L WangL Zheng
May 1, 1997·Physics in Medicine and Biology·S R Arridge, J C Hebden
Mar 21, 1988·Physical Review Letters·D J PineE Herbolzheimer
Aug 28, 1995·Physical Review Letters·D A BoasA G Yodh
Aug 7, 2003·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Joseph P CulverA G Yodh
Oct 9, 2007·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·M Vardi, A Nini
Aug 15, 2008·Physics in Medicine and Biology·Emil Y Sidky, Xiaochuan Pan
Dec 17, 2009·British Journal of Anaesthesia·J M Murkin, M Arango
Aug 15, 2008·Communications in Numerical Methods in Engineering·Hamid DehghaniKeith D Paulsen
Oct 19, 2011·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Marco FerrariValentina Quaresima
Aug 2, 2014·Nature Photonics·Adam T EggebrechtJoseph P Culver
Jul 1, 2010·Reports on Progress in Physics·T DurduranA G Yodh
Aug 12, 2015·Journal of Biomedical Optics·Lian HeGuoqiang Yu

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Citations

Jan 12, 2019·Science·Nur Arafeh-DalmauHugh Possingham
May 9, 2019·Biomedical Optics Express·Peng ZhangYu Shang

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