Nuchal translucency measurements: frequency distribution and changes with gestation in a general population

British Journal of Obstetrics and Gynaecology
J M BraithwaiteD L Economides

Abstract

To investigate nuchal translucency variation with crown-rump length (CRL) in the first trimester in normal fetuses. A prospective observational study. Department of obstetrics in a London teaching hospital. One thousand seven hundred and seven pregnant women (1685 singleton and 22 twin pregnancies) with chromosomally normal fetuses between 9+zero and 14+6 weeks of gestation were recruited sequentially from a dating scan clinic. Nuchal translucency was measured in 94.9% by transabdominal sonography (TAS) and by transvaginal sonography (TVS) if difficulty was encountered with TAS (5.1%). Nuchal translucency measurement was repeated in 136 fetuses: the first scan between between 9+zero-11+6 weeks and the second over 12 weeks of gestation. Of this general population, 4.2% had a nuchal translucency (NT) measurement > or = 2.5 mm, but this proportion varied significantly between gestational age groups (P = 0.011). The repeatability coefficients for NT measurements were 0.44 mm and 0.23 mm for TAS and TVS, respectively. The cross-sectional data demonstrate an increase in nuchal translucency measurement between 9 and 12 weeks of gestation and then a decrease at 13-14 weeks. This relation is best modelled using the quadratic equation: l...Continue Reading

References

Sep 1, 1975·British Journal of Obstetrics and Gynaecology·H P Robinson, J E Fleming
May 1, 1995·British Journal of Obstetrics and Gynaecology·L J RobertsC H Rodeck
May 1, 1995·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·P P PandyaK H Nicolaides
Jan 1, 1995·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·P P PandyaK H Nicolaides
Jan 1, 1995·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·C ComasA Fortuny
Jan 1, 1995·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·B BrambatiG Zuliani
Sep 1, 1994·British Journal of Obstetrics and Gynaecology·K H NicolaidesR J Snijders
Jan 1, 1993·American Journal of Obstetrics and Gynecology·M P JohnsonM I Evans
Sep 1, 1996·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J M BraithwaiteD L Economides

❮ Previous
Next ❯

Citations

Jul 19, 2002·Prenatal Diagnosis·Min ChenSai Fun Wong
Mar 3, 2007·Archives of Gynecology and Obstetrics·Peter SchmidtAlexander Scharf
Jan 17, 2014·Journal of Obstetrics and Gynaecology of India·Shailesh KoreY S Nandanwar
Mar 17, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·H J JouF J Hsieh
Dec 4, 1997·The New England Journal of Medicine·J W Seeds
Oct 9, 2002·Clinical Obstetrics and Gynecology·Renu BindraKypros H Nicolaides
Jul 20, 2010·Clinics in Laboratory Medicine·J Sonek, K Nicolaides
May 25, 2007·Gynécologie, obstétrique & fertilité·M-V Senat, R Frydman
Feb 2, 2013·Acta Obstetricia Et Gynecologica Scandinavica·Sini PeuhkurinenJaana Marttala
Sep 4, 2010·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·G GrangéO Morel
Aug 6, 2004·American Journal of Obstetrics and Gynecology·Kypros H Nicolaides
Jul 22, 2015·Journal of Medical Screening·Christina Unger LithnerSverker Ek
Feb 15, 2001·São Paulo Medical Journal = Revista Paulista De Medicina·G L AcácioM Faria
Mar 1, 2005·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·P W HuiP C Ho
Jun 1, 2006·Current Opinion in Obstetrics & Gynecology·Pui Wah HuiPak Chung Ho
Jul 30, 1999·British Journal of Obstetrics and Gynaecology·D L EconomidesJ M Braithwaite
Sep 24, 1998·British Journal of Obstetrics and Gynaecology·B J WhitlowD L Economides
Feb 23, 2018·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Debbie NisbetAndrew Mclennan
Jan 27, 1998·British Journal of Obstetrics and Gynaecology·D L EconomidesS M Verdin
Jul 1, 1998·British Journal of Obstetrics and Gynaecology·J C DornanC A Bailie
Aug 17, 2019·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Ismail Tekesin
Nov 8, 2019·Fetal and Pediatric Pathology·Ozgur OzyuncuOzgur Deren
May 1, 2002·Prenatal Diagnosis·Kypros H NicolaidesSimona Cicero
Jun 18, 2021·The Kurume Medical Journal·Toshiyuki YoshizatoKimio Ushijima

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

British Journal of Obstetrics and Gynaecology
B J WhitlowD L Economides
Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
J M BraithwaiteD L Economides
Baillière's Clinical Obstetrics and Gynaecology
N J Sebire, Kypros H Nicolaides
Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
A P SoukaKypros H Nicolaides
© 2021 Meta ULC. All rights reserved