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Nuclear factor E2-related factor-2 has a differential impact on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells: a condition favoring metabolic symbiosis between colorectal cancer and stromal cells

Oncogene

Aug 29, 2017

K DiehlHeiner Schäfer

Abstract

Malignant tumors, such as colorectal cancer (CRC), are heterogeneous diseases characterized by distinct metabolic phenotypes. These include Warburg- and reverse Warburg phenotypes depending on differential distribution of the lactate carrier proteins monocarboxylate transporter-4 and -1...read more

Mentioned in this Paper

GABPA gene
LDHB gene
NFE2L2 gene
SLC16A1 gene
SLC16A3 gene
SLC16A4 gene
MCTS1 gene
Slc16a1 protein, mouse
Lactic Acid Measurement
Immunohistochemistry
4
26
Paper Details
References
  • References63
  • Citations1
12345...

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Nuclear factor E2-related factor-2 has a differential impact on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells: a condition favoring metabolic symbiosis between colorectal cancer and stromal cells

Oncogene

Aug 29, 2017

K DiehlHeiner Schäfer

PMID: 28846107

DOI: 10.1038/onc.2017.299

Abstract

Malignant tumors, such as colorectal cancer (CRC), are heterogeneous diseases characterized by distinct metabolic phenotypes. These include Warburg- and reverse Warburg phenotypes depending on differential distribution of the lactate carrier proteins monocarboxylate transporter-4 and -1...read more

Mentioned in this Paper

GABPA gene
LDHB gene
NFE2L2 gene
SLC16A1 gene
SLC16A3 gene
SLC16A4 gene
MCTS1 gene
Slc16a1 protein, mouse
Lactic Acid Measurement
Immunohistochemistry
4
26

Similar Papers Found In These Feeds

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Paper Details
References
  • References63
  • Citations1
12345...
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