Abstract
Current techniques for left ventricular (LV) lead implantation in patients with ischemic cardiomyopathy (ICM) typically underutilize information which is important for optimal lead location, including LV mechanical activation pattern and scar location. We sought to develop a technique in which this information, contained in single-photon emission computed tomographic (SPECT) images, could be integrated as to guide the electrophysiologist during the implantation procedure. Five ICM patients underwent SPECT as well as multidetector cardiac computed tomographic (MDCT) imaging prior to the LV lead implantation procedure. Images were merged to create a "fusion" image, in which the SPECT data were projected onto the anatomically accurate MDCT epicardial surface. The fusion image was registered to the operative field using the coronary veins, apparent on the MDCT image, as a fiducial system. After registration, LV lead implantation was guided by the fusion image using a commercial catheter navigation system. Successful guidance was achieved in each patient, with minimal disturbance to standard workflow. Leads were implanted in late-activating, unscarred regions according to the fusion image, with locations corroborated by fluoroscopic...Continue Reading
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