PMID: 9440044Jan 24, 1998Paper

Nuclear magnetic resonance spectroscopy of mussel adhesive protein repeating peptide segment

The Journal of Peptide Research : Official Journal of the American Peptide Society
M P OlivieriJ L Alderfer

Abstract

Mussel adhesive protein (MAP) is the adhesive agent used by the common blue sea mussel (Mytilus edulis) to attach the animal to various underwater surfaces. It is generally composed of 75 to 85 repeating decameric units with the reported primary sequence NH2-Ala(1)-Lyst(2)-Pro(3)-Ser(4)-Tyr(5)-Hyp(6)-Hyp(7)-Thr(8)-DOPA( 9)- Lys(10)-COOH. This study examines this peptide's solution-state conformation using proton nuclear magnetic resonance (NMR) spectroscopy. NMR and molecular modeling of the decamer before and after molecular dynamics calculations in water suggests a conformation that retains an overall bent helix.

References

Jan 1, 1992·Biomaterials·M P OlivieriR E Loomis
Jul 1, 1991·International Journal of Peptide and Protein Research·P I NagyA J Hopfinger
Mar 1, 1989·Archives of Biochemistry and Biophysics·T WilliamsR W Henkens
Sep 10, 1985·Biochemistry·J H WaiteM L Tanzer

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Citations

Feb 22, 2013·Biopolymers·Manjeet DeshmukhArmin Geyer
Nov 23, 2012·Journal of the Royal Society, Interface·Qingye LuDong Soo Hwang
Aug 24, 2012·Protein Science : a Publication of the Protein Society·Dong Soo Hwang, J Herbert Waite
Jan 1, 2010·The Journal of Adhesion·Marion P OlivieriMichael F Swartz
Feb 17, 2017·The Journal of Experimental Biology·J Herbert Waite
Jul 25, 2008·Journal of Dental Research·N Holten-Andersen, J H Waite
Oct 12, 2004·Biomaterials·Sander HaemersGert Frens

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