Nuclear medicine in primary bone tumors

European Journal of Radiology
C FocacciP Campioni

Abstract

Conventional radiography is the method of choice to diagnose a primary bone tumor but in many cases it is necessary to integrate it with nuclear medicine scintigraphy using several radionuclides, including 67Ga, 201Tl, 99mTc-MIBI and especially 99mTc-diphosphonates. Recently a new technique has been recently introduced, that is positron emission tomography with 2(18F) fluoro-2 deoxy-D-glucose as radiopharmaceutical. The specific purpose of this work is to show that nuclear medicine bone scanning is a very important method in the detection and diagnostic management of primary bone tumors. DIAGNOSIS, STAGING AND FOLLOW-UP: Three-phase bone scintigraphy, integrated with SPECT, is clinically useful to confirm the radiologic diagnosis of bone tumor. These techniques conveniently related to each other and to radiographic findings, can evaluate the tumor's local aggressiveness, often differentiating benign from malignant lesions, to monitor treatment efficacy, to permit total body scanning for the detection of recurrences. Nuclear medicine diagnostic techniques are not in competition with radiographic tools as CT and MRI which are highly sensitive in detecting even small lesions thanks to their excellent anatomical resolution. In ques...Continue Reading

References

Nov 1, 1988·Clinical Nuclear Medicine·D Delbeke, M R Habibian
Jan 1, 1985·Skeletal Radiology·H T HarckeS Weiss
Jul 1, 1993·Clinical Nuclear Medicine·H Van der WallR L Philips

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Citations

Oct 26, 2011·Radiologic Clinics of North America·Flávia Martins CostaEmerson Gasparetto
Jun 16, 2011·Journal of the American Animal Hospital Association·Robert CruzJohn Urigh

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