Nuclear medicine in the era of genomics and proteomics: lessons from annexin V

Journal of Proteome Research
Tarik Z BelhocineFrancis G Blankenberg

Abstract

In the past decade, genomics and proteomics have begun to develop many new targets for potential diagnostic and therapeutic agents. Among the life sciences, nuclear medicine is also deeply involved in the field of clinical investigation. Experience with radiolabeled annexin V highlights the many steps required to translate a good basic-science concept into the clinical setting. This model also emphasizes the value of synergy between basic and medical specialties in developing and optimizing a clinically useful product initially derived from basic investigation.

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Citations

Dec 15, 2012·Apoptosis : an International Journal on Programmed Cell Death·Ming-Wei WangShu-Han Sun
Jan 6, 2011·Cancer Biotherapy & Radiopharmaceuticals·Janice KaptyJohn Mercer
Sep 28, 2010·Journal of Controlled Release : Official Journal of the Controlled Release Society·Kai WangByung-Heon Lee
Dec 6, 2005·Immunobiology·Anna Cederholm, Johan Frostegård
May 12, 2006·Organic & Biomolecular Chemistry·Kristy M DiVittorioBradley D Smith
Mar 4, 2021·Apoptosis : an International Journal on Programmed Cell Death·In-Seop SoYoung Mo Kang

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