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Nuclear Membrane-Targeted Gold Nanoparticles Inhibit Cancer Cell Migration and Invasion

ACS Nano

Mar 24, 2017

Moustafa R K AliMostafa A El-Sayed

Abstract

Most cancer patients die from metastasis. Recent studies have shown that gold nanoparticles (AuNPs) can slow down the migration/invasion speed of cancer cells and suppress metastasis. Since nuclear stiffness of the cell largely decreases cell migration, our hypothesis is that targeting ...read more

Mentioned in this Paper

Inner Nuclear Membrane
Study
Cell Motility
Nuclear Lamina
Cell Migration Inhibition Function
Ovarian Neoplasm
LMNA
Cell Nucleus
Cell Nucleus Structures
Microscopy, Atomic Force
11
2
89
Paper Details
References
  • References76
  • Citations5
12345...

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Nuclear Membrane-Targeted Gold Nanoparticles Inhibit Cancer Cell Migration and Invasion

ACS Nano

Mar 24, 2017

Moustafa R K AliMostafa A El-Sayed

PMID: 28333438

DOI: 10.1021/acsnano.6b08345

Abstract

Most cancer patients die from metastasis. Recent studies have shown that gold nanoparticles (AuNPs) can slow down the migration/invasion speed of cancer cells and suppress metastasis. Since nuclear stiffness of the cell largely decreases cell migration, our hypothesis is that targeting ...read more

Mentioned in this Paper

Inner Nuclear Membrane
Study
Cell Motility
Nuclear Lamina
Cell Migration Inhibition Function
Ovarian Neoplasm
LMNA
Cell Nucleus
Cell Nucleus Structures
Microscopy, Atomic Force
11
2
89

Related Papers

Paper Details
References
  • References76
  • Citations5
12345...
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