Nuclear Norm Clustering: a promising alternative method for clustering tasks

Scientific Reports
Yi WangLi Jin

Abstract

Clustering techniques are widely used in many applications. The goal of clustering is to identify patterns or groups of similar objects within a dataset of interest. However, many cluster methods are neither robust nor sensitive to noises and outliers in real data. In this paper, we present Nuclear Norm Clustering (NNC, available at https://sourceforge.net/projects/nnc/), an algorithm that can be used in various fields as a promising alternative to the k-means clustering method. The NNC algorithm requires users to provide a data matrix M and a desired number of cluster K. We employed simulated annealing techniques to choose an optimal label vector that minimizes nuclear norm of the pooled within cluster residual matrix. To evaluate the performance of the NNC algorithm, we compared the performance of both 15 public datasets and 2 genome-wide association studies (GWAS) on psoriasis, comparing our method with other classic methods. The results indicate that NNC method has a competitive performance in terms of F-score on 15 benchmarked public datasets and 2 psoriasis GWAS datasets. So NNC is a promising alternative method for clustering tasks.

References

Aug 30, 2000·Proceedings of the National Academy of Sciences of the United States of America·O AlterD Botstein
Apr 28, 2006·American Journal of Human Genetics·Rajan P NairJames T Elder
Jan 6, 2007·BMC Bioinformatics·Limin Fu, Enzo Medico
Jun 28, 2007·Biomedical Engineering Online·Max A LittleIrene M Moroz
May 13, 1983·Science·S KirkpatrickM P Vecchi
Jan 11, 2011·BMC Dermatology·Shenying FangMomiao Xiong
Mar 9, 2013·Journal of Chemical Information and Modeling·Kamel MansouriViviana Consonni
Jun 28, 2014·Science·Alex Rodriguez, Alessandro Laio
Sep 22, 2015·Nature Methods·Christian WiwieRichard Röttger
Jul 23, 2016·Scientific Reports·Yi WangLi Jin

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Citations

Jul 17, 2019·BMC Bioinformatics·Bruno Thiago de Lima NichioRoberto Tadeu Raittz
Jun 3, 2021·Genes·Andrés J Cortés, Felipe López-Hernández

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Software Mentioned

Clusterdp
factoextra
NNC
DBSCAN
densityClust
PAM
Hcluster
Clustering Large Applications ( CLARA )
CLARA
DIANA

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