Nuclear receptors and disease: androgen receptor

Essays in Biochemistry
Bruce GottliebMark Trifiro

Abstract

The death of cells by apoptosis is a fundamental event in development and the maintenance of cell homoeostasis. The other side of the coin, however, is that excessive cell death by apoptosis or the lack of apoptosis is often the driving force of many diseases. Whereas reduced apoptosis sensitivity is a basic characteristic of many tumour cells, accelerated tissue cell death and loss of tissue functions is the underlying cause of many auto-immune and inflammatory diseases.

Citations

Dec 13, 2005·Andrologia·B Haendler
Apr 19, 2007·Prostate Cancer and Prostatic Diseases·K SircarM Trifiro
Nov 19, 2011·Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation·T RévayW A King
Jan 5, 2011·Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation·D A F VillagómezW A King
May 5, 2011·Cancer Biotherapy & Radiopharmaceuticals·Xu-Bao ShiRalph W deVere White
Aug 1, 2018·Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation·Françoise ParisPatrick Balaguer
May 20, 2016·Expert Opinion on Therapeutic Targets·Sugunadevi SakkiahHuixiao Hong
Nov 21, 2017·Cancer Letters·Sanjay KumarManoj Mishra
Jul 3, 2010·Biochemistry·Brian J DeeganAmjad Farooq
Feb 17, 2010·Steroids·Daniel B Martinez-Arguelles, Vassilios Papadopoulos

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Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

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